Germline PARP4 mutations in patients with primary thyroid and breast cancers.

cognitive impairment is a common and disabling problem in Parkinson’s disease (PD). Identification of genetic variants that influence the presence or severity of cognitive deficits in PD may provide a clearer understanding of the underlying pathophysiology nonmotor this important feature. We genotypes 1105 PD patients of PD cognitive Genetics Consortium for variants using arrays NeuroX 249 336.

Participants assessment is doing the learning and memory (Hopkins Verbal Learning Test-Revised [HVLT-R]), working memory / executive function (Letter-Number Sequencing and Trail Making Test [TMT] A and B), language processing (semantic and phonemic verbal fluency ), visuospatial ability (Benton Judgment Line Orientation [Jolo]), and global cognitive function (Montreal cognitive Assessment).

For common variants, we used linear regression to test for association between genotype and cognitive performance with adjustment for important covariates. Rare variants were analyzed using a unified optimal kernel association test sequence. Threshold of significance was defined as a false discovery rate of corrected p-value (PFDR) 0.05. Eighteen common variants in 13 regions of the genome exceeds the threshold of significance for any of the cognitive tests.

This includes GBA rs2230288 (E326K; PFDR = 2.7 × 10-4) to Jolo, PARP4 rs9318600 (PFDR = 0.006), and rs9581094 (PFDR = 0.006) for HVLT-R total recall, and MTCL1 rs34877994 (PFDR = 0, 01) for TMT BA. Rare variant analysis did not produce significant gene region. We have conducted the first analysis of large-scale genetic PD cognitive and nominated some new suspected susceptibility genes for cognitive decline in PD. These results will require replication in an independent cohort of PD.

Germline PARP4 mutations in patients with primary thyroid and breast cancers.
Germline PARP4 mutations in patients with primary thyroid and breast cancers.

PARP4 germline mutations in patients with primary thyroid and breast cancer.

Germline mutations in the PTEN gene, which causes Cowden syndrome, which is known as one of the main genetic factor for thyroid and breast cancer; However, PTEN mutations are found in only a small proportion of study participants with non-syndrome, breast and thyroid cancer. In this study, we aimed to identify germline variants that may be associated with a major genetic risk of thyroid and breast cancer. Genomic DNA was extracted from peripheral blood of study participants WT PTEN 14 women with primary thyroid and breast cancer were analyzed by whole exome sequencing.

gene-based case-control association analysis using information from 406 Europeans were obtained from the 1000 Genome Project database identified 34 genes that might be associated with a phenotype with P <1.0 × 10 (-3). Among them, the rare variants in genes significantly PARP4 detected at high frequency (odds ratio = 5.2; P = 1.0 × 10 (-5)). Varian, G496V and T1170I, was found in six of the 14 study participants (43%) while only 0.5% of their frequency in the control.

functional analysis using the HCC1143 cell line showed that siRNA knockdown of PARP4 to significantly enhance cell proliferation compared to cells transfected with siControl (P = 0.02). Kaplan-Meier analysis using the Gene Expression Omnibus (GEO), the European Genome-phenome Archive (EGA) and The Cancer Genome Atlas (TCGA) dataset poor showing relapse-free survival (P <0.001, hazard ratio 1.27) and survival overall (P = 0.006, hazard ratio 1.41) in the low expression group PARP4, indicating that PARP4 may function as a tumor suppressor.

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

RD-PARP4-Hu-48Tests 48 Tests
EUR 625.2

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

RD-PARP4-Hu-96Tests 96 Tests
EUR 867.6

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

RDR-PARP4-Hu-48Tests 48 Tests
EUR 652.8

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

RDR-PARP4-Hu-96Tests 96 Tests
EUR 907.2

PARP4 antibody

70R-33845 100 ug
EUR 392.4
Description: Rabbit polyclonal PARP4 antibody

PARP4 Antibody

37796-100ul 100ul
EUR 302.4

PARP4 antibody

10R-1680 100 ug
EUR 614.4
Description: Mouse monoclonal PARP4 antibody

PARP4 Antibody

ABD2386 100 ug
EUR 525.6

PARP4 Antibody

1-CSB-PA947926
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against PARP4. Recognizes PARP4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

PARP4 Antibody

DF2386 200ul
EUR 420

PARP4 Antibody

1-CSB-PA007321
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PARP4. Recognizes PARP4 from Human. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

PARP4 Conjugated Antibody

C37796 100ul
EUR 476.4

Anti-PARP4 antibody

STJ110641 100 µl
EUR 332.4
Description: This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.

Anti-PARP4 antibody

STJ119167 100 µl
EUR 332.4

PARP4 siRNA

20-abx927766
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

anti-PARP4

YF-PA23186 50 ul
EUR 400.8
Description: Mouse polyclonal to PARP4

PARP4 Rabbit pAb

A16749-100ul 100 ul
EUR 369.6

PARP4 Rabbit pAb

A16749-200ul 200 ul
EUR 550.8

PARP4 Rabbit pAb

A16749-20ul 20 ul
EUR 219.6

PARP4 Rabbit pAb

A16749-50ul 50 ul
EUR 267.6

PARP4 Rabbit pAb

A8343-100ul 100 ul
EUR 369.6

PARP4 Rabbit pAb

A8343-200ul 200 ul
EUR 550.8

PARP4 Rabbit pAb

A8343-20ul 20 ul
EUR 219.6

PARP4 Rabbit pAb

A8343-50ul 50 ul
EUR 267.6

PARP4 Blocking Peptide

DF2386-BP 1mg
EUR 234

Human PARP4 shRNA Plasmid

20-abx950100
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

PARP4 ELISA KIT|Human

EF007039 96 Tests
EUR 826.8

Poly ADP Ribose Polymerase 4 (PARP4) Antibody

abx147654-100ug 100 ug
EUR 526.8

Poly ADP Ribose Polymerase 4 (PARP4) Antibody

20-abx006130
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Poly ADP Ribose Polymerase 4 (PARP4) Antibody

20-abx119585
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Poly ADP Ribose Polymerase 4 (PARP4) Antibody

20-abx128291
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Poly ADP Ribose Polymerase 4 (PARP4) Antibody

20-abx322903
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Poly ADP Ribose Polymerase 4 (PARP4) Antibody

20-abx339348
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Poly ADP Ribose Polymerase 4 (PARP4) Antibody

20-abx174132
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

PARP4 ORF Vector (Human) (pORF)

ORF027423 1.0 ug DNA
EUR 486

Parp4 ORF Vector (Mouse) (pORF)

ORF053400 1.0 ug DNA
EUR 1886.4

PARP4 ELISA Kit (Human) (OKCD08347)

OKCD08347 96 Wells
EUR 1170
Description: Description of target: This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.061ng/mL

PARP4 ELISA Kit (Human) (OKDD00456)

OKDD00456 96 Wells
EUR 1170
Description: Description of target: This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.;Species reactivity: Human;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: < 0.061 ng/mL

PARP4-AS1 ORF Vector (Human) (pORF)

ORF027424 1.0 ug DNA Ask for price

PARP4 sgRNA CRISPR Lentivector set (Human)

K1595801 3 x 1.0 ug
EUR 406.8

Parp4 sgRNA CRISPR Lentivector set (Mouse)

K4858201 3 x 1.0 ug
EUR 406.8

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody (Human)

4-PAC984Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase 4 (PARP4)

PARP4 sgRNA CRISPR Lentivector (Human) (Target 1)

K1595802 1.0 ug DNA
EUR 184.8

PARP4 sgRNA CRISPR Lentivector (Human) (Target 2)

K1595803 1.0 ug DNA
EUR 184.8

PARP4 sgRNA CRISPR Lentivector (Human) (Target 3)

K1595804 1.0 ug DNA
EUR 184.8

Parp4 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4858202 1.0 ug DNA
EUR 184.8

Parp4 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4858203 1.0 ug DNA
EUR 184.8

Parp4 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4858204 1.0 ug DNA
EUR 184.8

PARP4 Protein Vector (Human) (pPB-C-His)

PV109690 500 ng Ask for price

PARP4 Protein Vector (Human) (pPB-N-His)

PV109691 500 ng Ask for price

PARP4 Protein Vector (Human) (pPM-C-HA)

PV109692 500 ng Ask for price

PARP4 Protein Vector (Human) (pPM-C-His)

PV109693 500 ng Ask for price

PARP4 Protein Vector (Mouse) (pPB-C-His)

PV213598 500 ng
EUR 3902.4

PARP4 Protein Vector (Mouse) (pPB-N-His)

PV213599 500 ng
EUR 3902.4

PARP4 Protein Vector (Mouse) (pPM-C-HA)

PV213600 500 ng
EUR 3902.4

PARP4 Protein Vector (Mouse) (pPM-C-His)

PV213601 500 ng
EUR 3902.4

Recombinant Poly ADP Ribose Polymerase 4 (PARP4)

4-RPC984Hu01
  • EUR 550.08
  • EUR 271.20
  • EUR 1732.80
  • EUR 657.60
  • EUR 1195.20
  • EUR 444.00
  • EUR 4152.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Poly ADP Ribose Polymerase 4 expressed in: E.coli

PARP4 3'UTR Luciferase Stable Cell Line

TU017410 1.0 ml
EUR 1672.8

PARP4 3'UTR GFP Stable Cell Line

TU067410 1.0 ml
EUR 1672.8

Parp4 3'UTR GFP Stable Cell Line

TU165923 1.0 ml Ask for price

Parp4 3'UTR Luciferase Stable Cell Line

TU115923 1.0 ml Ask for price

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody (Human), APC

4-PAC984Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase 4 (PARP4). This antibody is labeled with APC.

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody (Human), Biotinylated

4-PAC984Hu01-Biotin
  • EUR 373.20
  • EUR 2952.00
  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase 4 (PARP4). This antibody is labeled with Biotin.

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody (Human), Cy3

4-PAC984Hu01-Cy3
  • EUR 502.80
  • EUR 5190.00
  • EUR 1410.00
  • EUR 654.00
  • EUR 301.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase 4 (PARP4). This antibody is labeled with Cy3.

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody (Human), FITC

4-PAC984Hu01-FITC
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase 4 (PARP4). This antibody is labeled with FITC.

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody (Human), HRP

4-PAC984Hu01-HRP
  • EUR 379.20
  • EUR 3426.00
  • EUR 968.40
  • EUR 477.60
  • EUR 247.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase 4 (PARP4). This antibody is labeled with HRP.

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody (Human), PE

4-PAC984Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase 4 (PARP4). This antibody is labeled with PE.

Human Poly ADP Ribose Polymerase 4 (PARP4) Protein

20-abx166526
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody (Human), APC-Cy7

4-PAC984Hu01-APC-Cy7
  • EUR 685.20
  • EUR 7716.00
  • EUR 2046.00
  • EUR 912.00
  • EUR 382.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase 4 (PARP4). This antibody is labeled with APC-Cy7.

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

20-abx152651
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Poly ADP Ribose Polymerase 4 (PARP4) CLIA Kit

abx197521-96tests 96 tests
EUR 990

Monkey Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

abx358874-96tests 96 tests
EUR 990

Rabbit Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

abx363456-96tests 96 tests
EUR 990

Pig Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

abx360853-96tests 96 tests
EUR 990

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

abx252901-96tests 96 tests
EUR 848.4

Chicken Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

abx355780-96tests 96 tests
EUR 990

Human Poly ADP Ribose Polymerase 4 (PARP4) CLIA Kit

20-abx494031
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human PARP4(Poly ADP Ribose Polymerase 4) ELISA Kit

EH3510 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

PARP4-AS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739631 1.0 ug DNA Ask for price

PARP4-AS1 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

LV739635 1.0 ug DNA Ask for price

PARP4-AS1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV739636 1.0 ug DNA Ask for price

Human Poly [ADP- ribose] polymerase 4, PARP4 ELISA KIT

ELI-12310h 96 Tests
EUR 988.8

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

SEC984Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poly ADP Ribose Polymerase 4 (PARP4) in Tissue homogenates and other biological fluids.

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

SEC984Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poly ADP Ribose Polymerase 4 (PARP4) in Tissue homogenates and other biological fluids.

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

SEC984Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poly ADP Ribose Polymerase 4 (PARP4) in Tissue homogenates and other biological fluids.

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

SEC984Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poly ADP Ribose Polymerase 4 (PARP4) in Tissue homogenates and other biological fluids.

Human Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit

4-SEC984Hu
  • EUR 5738.40
  • EUR 3031.20
  • EUR 768.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Poly ADP Ribose Polymerase 4 (PARP4) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

CLIA kit for Human PARP4 (Poly ADP Ribose Polymerase 4)

E-CL-H1422 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human PARP4 (Poly ADP Ribose Polymerase 4) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human PARP4 (Poly ADP Ribose Polymerase 4)

ELK3564 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Poly ADP Ribose Polymerase 4 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

PARP4 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K1595805 3 x 1.0 ug
EUR 451.2

Parp4 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4858205 3 x 1.0 ug
EUR 451.2

ELISA kit for Human PARP4 (Poly ADP Ribose Polymerase 4)

E-EL-H2420 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human PARP4 (Poly ADP Ribose Polymerase 4) in samples from Serum, Plasma, Cell supernatant

PARP4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K1595806 1.0 ug DNA
EUR 200.4

PARP4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K1595807 1.0 ug DNA
EUR 200.4

PARP4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K1595808 1.0 ug DNA
EUR 200.4

Parp4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4858206 1.0 ug DNA
EUR 200.4

Parp4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4858207 1.0 ug DNA
EUR 200.4

Parp4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4858208 1.0 ug DNA
EUR 200.4

PARP4-AS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV739632 1.0 ug DNA Ask for price

PARP4-AS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV739633 1.0 ug DNA Ask for price

PARP4-AS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV739634 1.0 ug DNA Ask for price

CD11b Antibody Antibody

ABD2911 100 ug
EUR 525.6

ASAP1 antibody Antibody

DF8746 200ul
EUR 420

anti- Antibody^Polyclonal antibody control antibody

LSMab09882 100 ug
EUR 525.6

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.08ML 0.08 ml
EUR 165

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.4ML 0.4 ml
EUR 379

Antibody

A1360-500 Ask for price

Anti-Glycolipid Antibody (AGA) Antibody

20-abx004855
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx008109
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx123734
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx014333
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-400ul 400 ul
EUR 627.6

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-80l 80 µl
EUR 343.2

Anti-Glycolipid Antibody (AGA) Antibody

abx036399-100ug 100 ug
EUR 469.2

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319900
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319901
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319905
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319913
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycolipid Antibody (AGA) Antibody

abx230204-100ug 100 ug
EUR 577.2

Ly1 Antibody Reactive (LYAR) Antibody

20-abx324434
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

20-abx311665
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

abx234901-100ug 100 ug
EUR 661.2

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 332.4

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 332.4

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 332.4

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

CLCN5 Antibody / CIC-5 antibody

RQ6462 100ug
EUR 419
Description: The CLCN5 gene encodes the chloride channel Cl-/H+ exchanger ClC-5. This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody

48169-100ul 100ul
EUR 399.6

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody

48169-50ul 50ul
EUR 286.8

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-01mg 0,1 mg
EUR 321
Description: anti-CD22 monoclonal antibody

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-1000ug 1000 ug
EUR 1539
Description: anti-CD22 monoclonal antibody

Antibody Pair to ApoA-V antibody

10R-1876 100 ul
EUR 781.2
Description: Mouse monoclonal Antibody Pair to ApoA-V antibody

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103034
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103035
  • EUR 560.40
  • EUR 159.60
  • EUR 1612.80
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103036
  • EUR 577.20
  • EUR 159.60
  • EUR 1696.80
  • EUR 794.40
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatitis C Virus Antibody (HCV) Antibody

abx023924-1mg 1 mg
EUR 1446

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319902
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319903
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319904
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319906
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319907
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

In conclusion, we identified susceptibility genes possibility PARP4 as the primary thyroid and breast cancer.