CD178 ELISpot Assay Kit (Human) (OKDB00015) |
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OKDB00015 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
|
Description: Description of target: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
Assay Elisa Laboratories manufactures the elisa assay protocol|elispot assay reagents distributed by Genprice. The Elisa Assay Protocol|Elispot Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Assay elisa. Other Elisa products are available in stock. Specificity: Elisa Category: Assay Group: Protocol|Elispot Assay
IL-10 ELISpot Assay Kit (Human) (OKDB00007) |
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Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
|
Description: Description of target: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
TNF alpha ELISpot Assay Kit (Human) (OKDB00009) |
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Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
|
Description: Description of target: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IFN gamma ELISpot Assay Kit (Human) (OKDB00011) |
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Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
|
Description: Description of target: This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IL-12 ELISpot Assay Kit (Human) (OKDB00013) |
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Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
|
Description: Description of target: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IL-5 ELISpot Assay Kit (Human) (OKDB00019) |
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Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
|
Description: Description of target: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IL-13 ELISpot Assay Kit (Human) (OKDB00021) |
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Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
|
Description: Description of target: This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
Granzyme B ELISpot Assay Kit (Human) (OKDB00023) |
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Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
|
Description: Description of target: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IL-17A ELISpot Assay Kit (Human) (OKDB00027) |
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Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
|
Description: Description of target: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
Protocol|Elispot Assay information
TNF alpha ELISpot Assay Kit (Rat) (OKDB00039) |
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OKDB00039 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
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Description: Description of target: acts as a cytokine; binds TNF receptors; plays a role in regulation of cell proliferation, induction of apoptosis, and inflammatory response [RGD, Feb 2006];Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IL-17A ELISpot Assay Kit (Human) (OKDB00027) |
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OKDB00027 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
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Description: Description of target: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IL-17F ELISpot Assay Kit (Human) (OKDB00029) |
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OKDB00029 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
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Description: Description of target: The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
TNF alpha ELISpot Assay Kit (Human) (OKDB00009) |
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OKDB00009 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
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Description: Description of target: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IFN gamma ELISpot Assay Kit (Human) (OKDB00011) |
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OKDB00011 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
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Description: Description of target: This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IFN gamma ELISpot Assay Kit (Murine) (OKDB00035) |
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OKDB00035 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
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Description: Description of target: This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mice deficient in this gene have increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.;Species reactivity: Murine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
Granzyme B ELISpot Assay Kit (Human) (OKDB00023) |
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OKDB00023 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
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Description: Description of target: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
OKDB00015-5X96W - CD178 ELISpot Assay Kit (Human) |
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OKDB00015-5X96W |
Aviva Systems Biology |
5x96Wells |
EUR 1259 |
|
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OKDB00025-5X96W - Perforin ELISpot Assay Kit (Human) |
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OKDB00025-5X96W |
Aviva Systems Biology |
5x96Wells |
EUR 1259 |
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IL-1 beta ELISpot Assay Kit (Human) (OKDB00017) |
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OKDB00017 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
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Description: Description of target: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
IL-17A/F ELISpot Assay Kit (Human) (OKDB00031) |
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OKDB00031 |
Aviva Systems Biology |
1x96Wells |
EUR 638.4 |
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Description: Description of target: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity: |
OKDB00001-5X96W - IL-2 ELISpot Assay Kit (Human) |
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OKDB00001-5X96W |
Aviva Systems Biology |
5x96Wells |
EUR 1259 |
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OKDB00003-5X96W - IL-4 ELISpot Assay Kit (Human) |
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OKDB00003-5X96W |
Aviva Systems Biology |
5x96Wells |
EUR 1259 |
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OKDB00005-5X96W - IL-6 ELISpot Assay Kit (Human) |
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OKDB00005-5X96W |
Aviva Systems Biology |
5x96Wells |
EUR 1259 |
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OKDB00019-5X96W - IL-5 ELISpot Assay Kit (Human) |
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OKDB00019-5X96W |
Aviva Systems Biology |
5x96Wells |
EUR 1259 |
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