Mouse Pd-L1 Purified Monoclonal Antibody

PD-L1 Monoclonal Antibody

CAC10271-100ul 100ul
EUR 367.5

Human IgG antibody Laboratories manufactures the mouse pd-l1 purified monoclonal antibody reagents distributed by Genprice. The Mouse Pd-L1 Purified Monoclonal Antibody reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact mouse monoclonal. Other Mouse products are available in stock. Specificity: Mouse Category: Pd-L1 Group: Purified Monoclonal

PD-L1 Antibody

0.1 mg
EUR 523.7
Description: PD-L1 plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, PD-L1 modulates the activation threshold of T-cells and limits T-cell effector response (1). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (2,3). Through a yet unknown activating receptor, it may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (4).

PD-L1 Antibody

100ul
EUR 399.6

PD-L1 Antibody

50ul
EUR 286.8

PD-L1 Antibody

0.1m
EUR 224.4

PD-L1 Antibody

1ml
EUR 807.6

PD-L1 Antibody

100ul
EUR 280
Description: Human,Mouse,Rat

PD-L1 Antibody

100 ug
EUR 356.15
Description: Programmed death-ligand 1, also known as CD274 or B7-H1 is a protein that in humans is encoded by the CD274 gene. It is a 33-70kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. Upregulation on tumor MDCs downregulates T-cell immunity and PD-L1 blockade may represent an approach for cancer immunotherapy. It can provide positive costimulatory signals for innate and adaptive immunity and for protection against intracellular bacterial infection. It has been found that PD1/PDL1 pathway may be a good target for restoring antitumor immunity in ovarian cancer.

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