Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression.

Apoptosis Ligand (Trail), Angonistic monoclonal antibodies to trail receptors and molecule trail receptor agonists are different from preclinical and pretty clinical trials as potential anti-cancer drugs. As a result, there is a substantial interest in understanding the factors that affect the sensitivity to these agents. In the present study, we observed that polymerase polymerase inhibitors (PARP-RIBOSE) Olaparib and Veliparib sensitize the cellular lines of myeloid leukemia ML-1 and K562, the ovarian cancer cancer line. Peo1, the A549 non-low cell lung cancer line, and a majority of clinical AML isolates, but no normal marrow, at the track.

Further analysis has shown that the processing of PARP inhibitor results in an activation of the promoters of the FAS and the TNFRSF10B (Death Receiver 5 (DR5)), increased FAS and DR5 mRNA and a surface expression of High cell of these receptors in sensitized cells. The immunoprecipitation of chromatin has demonstrated an improved connection of the SP1 transcription factor to the TNFRSF10B promoter in the presence of PARP inhibitor. The reversal of PARP1 or PARP2 not only has an increased expression of FAS and DR5 at the mRNA and the protein level, but also summarized the sensitization effects of the inhibition PARP. Conversely, SP1 Hashingdown has decreased the effects of Parp inhibitor. Given the fact that the trail is part of the armamentarium of natural killer cells, these observations identify a new facet of the action of inhibitor PARP while simultaneously providing the mechanistic sub-declarations of a new therapeutic combination that justifies a more in-depth investigation.

The rapid evolution of PARP genes suggests a broad role of FAD-ribosylation in host virus conflicts.

Changes in post-translational proteins such as phosphorylation and ubiquitinylation are common molecular objectives of conflict between viruses and their hosts. However, the role of other post-translational modifications, such as ADP-ribosylation, in earlier virus interactions, is less well characterized. The adp-ribosylation is carried out by proteins coded by the Gene PARP family (also called ArtD). The majority of 17 human Parp genes are poorly characterized. However, a PARP, PARP13 / ZAP protein, has extensive antiviral activity and has evolved into a positive selection (diversification) in primates. Such an evolution is typical of areas that are locked in antagonistic “breeds of weapons” with viral factors.

To identify additional PARP genes that can be involved in host virus interactions, we performed evolutionary analyzes on all Primates PARP genes to search for quick evolution signatures. Contrary to the expectations that most PARP genes are involved in “household” functions, we found that nearly one-third of PARP genes evolve in a selection of recurrent positive choices. We have identified a disordered region of 300 amino acids of PARP4, a component of cytoplasmic vault structures, in order to rapidly evolve into several mammalian lines, suggesting that this region serves as a significant interface for the specificity of the host-pathogen. . We also found a positive selection of PARP9, 14 and 15, the only three human genes containing both PARP domains and macrodomates.

Macrodomains recognize uniquely, and in some cases can reverse, mono-adp-ribosylation protein, and we have observed high recurring positive selection signatures in macro-PARP macrodomains. In addition, PARP14 and PARP15 suffered repeated turns of birth and loss of genes during the evolution of vertebrates, in accordance with recurring gene innovation. Together with previous studies that involved several parps in immunity, as well as those who have demonstrated a role of virically coded macrodomains in the immune escape of the host, our evolutionary analyzes suggest that the addition, recognition and The elimination of ADP-ribosylation are a critical and underestimated currency in the host. -Virus conflicts.

Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression.
Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression.

The sequencing of the capture of exode reveals new perspectives on hepatocellular carcinoma induced by the hepatitis B virus at the beginning of tumorigenesis.

Hepatocellular carcinoma (HCC), the most common liver cancer type, is the main leading cause of cancer mortality in the world. The molecular mechanisms underlying the initiation and training of HCC remain obscure. In this study, we performed an exome sequencing using normal tumors and tissues from 3 patients with possible Hepatitis B (HBV) BCCCs. The bioinformatic analysis was performed to find somatic mutations modifying candidate proteins. Eighty damaging mutations have been validated and 59 genes were to be transferred to HBV CCRs for the first time here.

Further analysis using entire genome sequencing data (WGS) of 88 HBV-related HCC patients from the European Genome-Phenomena archive database showed that mutations of 33 of the 59 genes have also been detected in other samples. Variants of two newly found genes, ZNF717 and PARP4 were detected in more than 10% of WGS samples. Several other genes, such as FLNA and CNTN2, are also remarkable. Thus, the sequencing analysis of the exode of three patients with BCLC a patient offers new perspectives in the molecular events governing the first steps of HCC tumorigenesis induced by the HBV. POLY Polymerase Catalyzes the formation of adap-ribose polymers attached covalently to proteins using NAD + as a substrate. PARP is strongly activated by DNA two-strand breaks and is considered involved in cell responses to DNA damage.

Human Jagged 1 Protein (JAG1) Protein

20-abx067570
  • EUR 727.20
  • EUR 309.60
  • EUR 2180.40
  • EUR 861.60
  • EUR 526.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Jagged 1 Protein (JAG1) Protein

20-abx067571
  • EUR 727.20
  • EUR 309.60
  • EUR 2180.40
  • EUR 861.60
  • EUR 526.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Jagged 1 Protein (JAG1) Protein

20-abx067572
  • EUR 727.20
  • EUR 309.60
  • EUR 2180.40
  • EUR 861.60
  • EUR 526.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Jagged 1 Protein (JAG1) Protein

20-abx165879
  • EUR 794.40
  • EUR 326.40
  • EUR 2448.00
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Protein jagged-1 (Jag1)

1-CSB-EP870758MO
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Protein jagged-1(Jag1),partial expressed in E.coli

Jagged 1 Protein (JAG1) Antibody

20-abx101519
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Jagged 1 Protein (JAG1) Antibody

20-abx173207
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Jagged 1 Protein (JAG1) Antibody

20-abx177228
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Jagged 1 Protein (JAG1) Antibody

20-abx101517
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Jagged 1 Protein (JAG1) Antibody

20-abx101518
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Jagged 1 Protein (JAG1) Antibody

20-abx129567
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Protein Jagged-1 (JAG1) Antibody

20-abx213868
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Protein Jagged-1 (JAG1) Antibody

20-abx214943
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Protein Jagged-1 (JAG1) Antibody

abx216340-100ug 100 ug
EUR 526.8

Protein Jagged-1 (JAG1) Antibody

20-abx327592
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Protein Jagged-1 (JAG1) Antibody

abx037271-100ug 100 ug
EUR 469.2

Protein Jagged-1 (JAG1) Antibody

abx038125-100ug 100 ug
EUR 469.2

Protein Jagged-1 (JAG1) Antibody

abx431368-200ul 200 ul
EUR 460.8

Protein Jagged-1 (JAG1) Antibody

20-abx302273
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant Jagged 1 Protein (JAG1)

4-RPB807Hu01
  • EUR 517.82
  • EUR 261.60
  • EUR 1611.84
  • EUR 617.28
  • EUR 1114.56
  • EUR 422.40
  • EUR 3849.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Jagged 1 Protein expressed in: E.coli

Recombinant Jagged 1 Protein (JAG1)

4-RPB807Hu02
  • EUR 517.82
  • EUR 261.60
  • EUR 1611.84
  • EUR 617.28
  • EUR 1114.56
  • EUR 422.40
  • EUR 3849.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Jagged 1 Protein expressed in: E.coli

Recombinant Jagged 1 Protein (JAG1)

4-RPB807Hu03
  • EUR 517.82
  • EUR 261.60
  • EUR 1611.84
  • EUR 617.28
  • EUR 1114.56
  • EUR 422.40
  • EUR 3849.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Jagged 1 Protein expressed in: E.coli

Recombinant Jagged 1 Protein (JAG1)

4-RPB807Mu01
  • EUR 571.58
  • EUR 276.00
  • EUR 1813.44
  • EUR 684.48
  • EUR 1248.96
  • EUR 458.40
  • EUR 4353.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Jagged 1 Protein expressed in: E.coli

Rat Jag1(Protein jagged-1) ELISA Kit

ER0639 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 46.9pg/ml

Rat Jag1/ Protein jagged-1 ELISA Kit

E0537Ra 1 Kit
EUR 685.2

Rat Jag1(Protein jagged-1) ELISA Kit

EKF58438-48T 48T
EUR 396.9

Rat Jag1(Protein jagged-1) ELISA Kit

EKF58438-5x96T 5x96T
EUR 2693.25

Rat Jag1(Protein jagged-1) ELISA Kit

EKF58438-96T 96T
EUR 567

Recombinant Human Jagged-1/JAG1 Protein

RP00877 10 μg
EUR 265.2

Mouse Jag1/ Protein jagged-1 ELISA Kit

E0818Mo 1 Kit
EUR 685.2

Human JAG1/ Protein jagged-1 ELISA Kit

E1358Hu 1 Kit
EUR 685.2

Protein Jagged-1 (JAG1) Antibody (HRP)

20-abx315963
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Jagged-1 (JAG1) Antibody (FITC)

20-abx315964
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Jagged 1 Protein (JAG1) Antibody (Biotin)

20-abx272192
  • EUR 526.80
  • EUR 292.80
  • EUR 1513.20
  • EUR 727.20
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Jagged 1 Protein (JAG1) Antibody (Biotin)

20-abx274491
  • EUR 526.80
  • EUR 292.80
  • EUR 1496.40
  • EUR 727.20
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Protein jagged- 1, Jag1 ELISA KIT

ELI-06944r 96 Tests
EUR 1063.2

Rat JAG1(Jagged 1 Protein) ELISA Kit

ELK9329-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat JAG1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat JAG1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat JAG1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat JAG1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat JAG1(Jagged 1 Protein) ELISA Kit

ELK9329-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat JAG1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat JAG1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat JAG1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat JAG1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Protein Jagged-1 (JAG1) Antibody (Biotin)

20-abx315965
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Protein jagged-1 (JAG1) ELISA Kit

abx256614-96tests 96 tests
EUR 801.6

Human Jagged 1 Protein (JAG1) CLIA Kit

20-abx493101
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Jagged 1 Protein (JAG1) CLIA Kit

20-abx493102
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Protein jagged-1 (JAG1) ELISA Kit

RK14543 96T
EUR 280

Human Jagged 1 Protein (JAG1) ELISA Kit

20-abx152071
  • EUR 8534.40
  • EUR 4550.40
  • EUR 1054.80
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Jagged 1 Protein (JAG1) ELISA Kit

20-abx154277
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Jagged 1 Protein (JAG1) ELISA Kit

DLR-JAG1-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Jagged 1 Protein (JAG1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

DLR-JAG1-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Jagged 1 Protein (JAG1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

DLR-JAG1-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Jagged 1 Protein (JAG1) in samples from tissue homogenates or other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

DLR-JAG1-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Jagged 1 Protein (JAG1) in samples from tissue homogenates or other biological fluids.

Human Jagged 1 Protein, JAG1 ELISA Kit

ELA-E2164h 96 Tests
EUR 988.8

Mouse Protein jagged- 1, Jag1 ELISA KIT

ELI-06945m 96 Tests
EUR 1038

Human Protein jagged- 1, JAG1 ELISA KIT

ELI-06946h 96 Tests
EUR 988.8

Human Jagged 1 Protein (JAG1) ELISA Kit

SEB807Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Jagged 1 Protein (JAG1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

SEB807Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Jagged 1 Protein (JAG1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

SEB807Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Jagged 1 Protein (JAG1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

SEB807Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Jagged 1 Protein (JAG1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

4-SEB807Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Jagged 1 Protein (JAG1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

SEB807Mu-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Jagged 1 Protein (JAG1) in Tissue homogenates and other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

SEB807Mu-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Jagged 1 Protein (JAG1) in Tissue homogenates and other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

SEB807Mu-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Jagged 1 Protein (JAG1) in Tissue homogenates and other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

SEB807Mu-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Jagged 1 Protein (JAG1) in Tissue homogenates and other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

4-SEB807Mu
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Jagged 1 Protein (JAG1) in samples from Tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Jagged 1 Protein ELISA Kit (JAG1)

RK01715 96 Tests
EUR 625.2

Human Jagged 1 Protein (JAG1) ELISA Kit

RDR-JAG1-Hu-48Tests 48 Tests
EUR 626.4

Human Jagged 1 Protein (JAG1) ELISA Kit

RDR-JAG1-Hu-96Tests 96 Tests
EUR 868.8

Mouse Jagged 1 Protein (JAG1) ELISA Kit

RDR-JAG1-Mu-48Tests 48 Tests
EUR 640.8

Mouse Jagged 1 Protein (JAG1) ELISA Kit

RDR-JAG1-Mu-96Tests 96 Tests
EUR 890.4

Mouse Jagged 1 Protein ELISA Kit (JAG1)

RK02964 96 Tests
EUR 625.2

Human Jagged 1 Protein(JAG1)ELISA Kit

QY-E04851 96T
EUR 472.8

Human Jagged 1 Protein (JAG1) ELISA Kit

RD-JAG1-Hu-48Tests 48 Tests
EUR 600

Human Jagged 1 Protein (JAG1) ELISA Kit

RD-JAG1-Hu-96Tests 96 Tests
EUR 830.4

Mouse Jagged 1 Protein (JAG1) ELISA Kit

RD-JAG1-Mu-48Tests 48 Tests
EUR 613.2

Mouse Jagged 1 Protein (JAG1) ELISA Kit

RD-JAG1-Mu-96Tests 96 Tests
EUR 850.8

Human Jagged 1 Protein (JAG1) ELISA Kit

RDR-JAG1-Hu-48T 48T
EUR 453.92
Description: serum, plasma, tissue homogenates and other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

RDR-JAG1-Hu-96T 96T
EUR 648.38
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

RDR-JAG1-Mu-48T 48T
EUR 465.47
Description: tissue homogenates and other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

RDR-JAG1-Mu-96T 96T
EUR 664.97
Description: tissue homogenates and other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

DL-JAG1-Hu 96T
EUR 421
Description: serum, plasma, tissue homogenates or other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

DL-JAG1-Mu 96T
EUR 432
Description: tissue homogenates or other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

DLR-JAG1-Hu 96T
EUR 443
Description: serum, plasma, tissue homogenates or other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

DLR-JAG1-Mu 96T
EUR 454
Description: tissue homogenates or other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

RD-JAG1-Hu-48T 48T
EUR 432.3
Description: serum, plasma, tissue homogenates and other biological fluids.

Human Jagged 1 Protein (JAG1) ELISA Kit

RD-JAG1-Hu-96T 96T
EUR 617.5
Description: serum, plasma, tissue homogenates and other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

RD-JAG1-Mu-48T 48T
EUR 443.3
Description: tissue homogenates and other biological fluids.

Mouse Jagged 1 Protein (JAG1) ELISA Kit

RD-JAG1-Mu-96T 96T
EUR 633.3
Description: tissue homogenates and other biological fluids.

Mouse JAG1(Jagged 1 Protein) ELISA Kit

ELK3597-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse JAG1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse JAG1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse JAG1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse JAG1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse JAG1(Jagged 1 Protein) ELISA Kit

ELK3597-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse JAG1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse JAG1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse JAG1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse JAG1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human JAG1(Jagged 1 Protein) ELISA Kit

ELK3156-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human JAG1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human JAG1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human JAG1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human JAG1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human JAG1(Jagged 1 Protein) ELISA Kit

ELK3156-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human JAG1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human JAG1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human JAG1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human JAG1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Protein jagged-1 (JAG1) ELISA Kit

abx570714-96tests 96 tests
EUR 801.6

Mouse Protein jagged-1 (JAG1) ELISA Kit

abx571056-96tests 96 tests
EUR 801.6

Human Protein jagged-1(JAG1) ELISA kit

CSB-EL011927HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Protein jagged-1 (JAG1) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Protein jagged-1(JAG1) ELISA kit

1-CSB-EL011927HU
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Protein jagged-1(JAG1) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Protein jagged-1(JAG1) ELISA kit

EKC41715-48T 48T
EUR 535.99

Human Protein jagged-1(JAG1) ELISA kit

EKC41715-5x96T 5x96T
EUR 3637.08

Human Protein jagged-1(JAG1) ELISA kit

EKC41715-96T 96T
EUR 765.7

Human Protein jagged-1(JAG1) ELISA kit

SL3699Hu 96 Tests
EUR 468

Mouse Protein jagged-1 (JAG1) ELISA Kit

RK13071 96T
EUR 280

Human Protein jagged-1 (JAG1) ELISA Kit

RK11128 96T
EUR 280

ELISA kit for Human JAG1 (Jagged 1 Protein)

ELK3156 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Jagged 1 Protein from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse JAG1 (Jagged 1 Protein)

ELK3597 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Jagged 1 Protein from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Human Jagged 1 / JAG1 Protein, His Tag, premium grade

JA1-H52H9 1mg
EUR 310.3
Description: Human Jagged 1, His Tag, premium grade (JA1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 34 - Ser 1046 (Accession # P78504-1).

Rat Protein jagged-1,JAG1/CD339 ELISA Kit

YLA1285RA-48T 48T
EUR 465

Rat Protein jagged-1,JAG1/CD339 ELISA Kit

YLA1285RA-96T 96T
EUR 600

Recombinant Human Jagged-1/JAG1 Protein, Fc His Tag

E40KMP1677 20ug
EUR 495

Human Protein jagged-1,JAG1/CD339 ELISA Kit

YLA1266HU-48T 48T
EUR 435

Human Protein jagged-1,JAG1/CD339 ELISA Kit

YLA1266HU-96T 96T
EUR 562.5

Mouse Protein jagged-1,JAG1/CD339 ELISA Kit

YLA1465MO-48T 48T
EUR 465

Mouse Protein jagged-1,JAG1/CD339 ELISA Kit

YLA1465MO-96T 96T
EUR 600

Jagged 1 Protein (JAG1) Polyclonal Antibody (Mouse)

4-PAB807Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Jagged 1 Protein (JAG1)

Rabbit Protein jagged-1(JAG1/CD339)ELISA Kit

YLA0006RB-48T 48T
EUR 465

Rabbit Protein jagged-1(JAG1/CD339)ELISA Kit

YLA0006RB-96T 96T
EUR 600

Protein Jagunal Homolog 1 (JAGN1) Antibody

20-abx302919
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Jagged 1 Recombinant Protein

96-482 0.05 mg
EUR 651.3
Description: Protein jagged-1 (JAG1) is also known as Jagged1, hJ1, JAGL1 and CD339, which is a single-pass type I membrane protein containing one DSL domain and 15 EGF-like domains. JAG1 is widely expressed in adult and fetal tissues,the expression of JAG1 is up-regulated in cervical squamous cell carcinoma and also expressed in bone marrow cell line HS-27a.JAG1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. JAG1 is involved in early and late stages of mammalian cardiovascular development. JAG1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).

Recombinant Mouse Protein jagged-1 (Jag1) ,partial

RPC20542-100ug 100ug
EUR 572

Recombinant Mouse Protein jagged-1 (Jag1) ,partial

RPC20542-1mg 1mg
EUR 2884.7

Recombinant Mouse Protein jagged-1 (Jag1) ,partial

RPC20542-20ug 20ug
EUR 353.4

Jagged-1 Recombinant Protein

90-084 10 ug
EUR 468.6
Description: Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).

Jagged-1 Recombinant Protein

90-085 50 ug
EUR 682.8
Description: Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).

jagged-1 Recombinant Protein

91-812 0.05 mg
EUR 739.5
Description: Protein jagged-1 I, also known as Jagged-1, JAGL1, HJ1, JAG1 and CD339, is a single-pass type I membrane protein. JAG1 contains one DSL domain and sixteen EGF-like domain. JAG1 acts as a ligand for multiple Notch receptors and is involved in the mediation of Notch signaling. JAG1 may participate in early and late stages of mammalian cardiovascular development, JAG1 inhibits myoblast differentiation and enhances fibroblast growth factor-induced angiogenesis. Defects in JAG1 are the cause of Alagille syndrome type 1, which is autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations.

Jag1 ELISA Kit| Rat Protein jagged-1 ELISA Kit

EF017455 96 Tests
EUR 826.8

Mouse Jagged 2 Protein (JAG2) Protein

20-abx067573
  • EUR 794.40
  • EUR 326.40
  • EUR 2431.20
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Jagged 2 Protein (JAG2) Protein

20-abx067574
  • EUR 760.80
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

We have characterized a dominant negative Parp mutant, that is to say the DNA binding domain of this enzyme, whose overexpression in cells results in increased genetic instability after damage to DNA. In order to study whether the PARP activity is also involved in the process of tumorigenesis, we have generated helical cell clones in a stable manner with a constitutive overexpression of the dominant negative PARP and a tumor formation examined with these clones in naked mice. .