Assessment of DNA repair susceptibility genes identified by whole exome sequencing in head and neck cancer.

We conduct exploratory biomarker study of a phase II clinical trial of eribulin plus gemcitabine (EG) versus paclitaxel plus gemcitabine (PG) in metastatic breast cancer HER2-negative (BC) patients.We conducted targeted deep sequencing with adjustable cancer gene panel and RNA expression assay. Tumor mutation load (TMB) and mutation signature is determined based on a genetic change in a targeted area. Gene variation analysis performed by PanCancer set Immune Pathway Profiling and PanCancer Panel.

Statistical analysis was performed to identify the relationship between genetic changes and clinical outcomes.Of 119 patients, 40 had a biomarker data available. Among the 40 patients, 4 post-treatment network support them. In targeted sequencing in, FAT3 (48%) is the most frequently mutated gene, followed by PKHD1, TP53, GATA3, PARP4, and PIK3CA. In terms of gene expression, low expression of epithelial-mesenchymal transition (EMT) pathway genes associated with prolonged progression-free survival (PFS) in the group EG, while high expression of EMT pathway is associated with a good prognosis in the PG group.

TMB median was 6.5 (range 2.44 to 46.34) and no association between TMB and the patient’s prognosis. Signature mutation analysis showed that the signature of 3, 20, and 26 which are often observed in our group. Survival analysis Furthermore, according to the signature mutations shows that mutations signature 3, as signature-related deficiencies homologous recombinant, it is strongly associated with disease progression (hazard ratio (log2 scale) 8:21, the 95% confidence interval 2.93 to 13.48 , p = 0.002).

Kaplan-Meier plot also shows that the BCs with signature 3 has a shorter PFS compared with those who did not sign this (median PFS (months) for signing 3 (low vs. high): 17.2 vs. 8.1, p = 0, 0026) .Mutation signature 3, found in about 30% of MBCS regardless of hormone receptor status, was associated with shorter PFS for patients with cytotoxic chemotherapy.

Assessment of DNA repair susceptibility genes identified by whole exome sequencing in head and neck cancer.
Assessment of DNA repair susceptibility genes identified by whole exome sequencing in head and neck cancer.

Modifications PARP4, XRCC3, and RAD51 Gene Polymorphism on the relationship between Bisphenol A Exposure and liver abnormalities.

repair genes may play an important role in the relationship between environmental exposures and health outcomes. However, no evidence was available about the effect of genetic polymorphisms on the improvement of the relationship between bisphenol A (BPA) exposure and liver abnormalities.

Therefore, we evaluated the effect of nine polymorphism genotypes in three genes repair, poly (ADP-ribose) member polymerase family of 4 (PARP4), X-ray repair cross-complementary 3 (XRCC3), and RAD51 recombinase (RAD51), in relation between exposure to BPA and heart abnormalities using repeated measures of data for the elderly population.

A significant association between BPA levels and liver abnormalities are found only in elders with PARP4 haplotype GCG, XRCC3 GAG haplotype, or RAD51 TAA haplotype (odds ratio (OR) = 2.16 and p = 0.0014 for PARP4; OR = 1.57 and p = 0.0249 for XRCC3; OR = 1.43 and p = 0.0422 for RAD51). Especially, PARP4 and XRCC3 showed significant interaction with BPA exposure in relation to liver abnormalities (p <0.05 for both genes). These results indicate that PARP4, XRCC3, and RAD51 gene polymorphism has the effect of modifications on the relationship between exposure to BPA and heart abnormalities.

Colorectal neuroendocrine tumors (nets) are rare neoplasms and study of colorectal nets is relatively small compared with other tumors. To better understand the pathogenesis of this tumor, we performed whole genome sequencing and follow-up verification using Sanger sequencing of colorectal and paired Nets para-tumor tissue.

PARP-4 Polyclonal Antibody

E20-73596 100ug
EUR 225
Description: Available in various conjugation types.

PARP-4 Polyclonal Antibody

E44H05803 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP-4 Polyclonal Antibody

MBS8524577-01mg 0.1mg
EUR 305

PARP-4 Polyclonal Antibody

MBS8524577-01mLAF405L 0.1mL(AF405L)
EUR 465

PARP-4 Polyclonal Antibody

MBS8524577-01mLAF405S 0.1mL(AF405S)
EUR 465

PARP-4 Polyclonal Antibody

MBS8524577-01mLAF610 0.1mL(AF610)
EUR 465

PARP-4 Polyclonal Antibody

MBS8524577-01mLAF635 0.1mL(AF635)
EUR 465

PARP-4 Polyclonal Antibody

UB-GEN-474 100 ul
EUR 200

PARP-4 Rabbit Polyclonal Antibody

ES4835-100ul 100ul
EUR 124
Description: IHC, ELISA

PARP-4 Rabbit Polyclonal Antibody

ES4835-50ul 50ul
EUR 74
Description: IHC, ELISA

PARP polyclonal antibody

BS91017 50ul
EUR 398
Description: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

PARP Polyclonal Antibody

MBS126121-002mL 0.02mL
EUR 200

PARP Polyclonal Antibody

MBS126121-005mL 0.05mL
EUR 295

PARP Polyclonal Antibody

MBS126121-01mL 0.1mL
EUR 420

PARP Polyclonal Antibody

MBS126121-02mL 0.2mL
EUR 600

PARP Polyclonal Antibody

MBS126121-5x02mL 5x0.2mL
EUR 2525

PARP polyclonal antibody

MBS565256-0025mL 0.025mL
EUR 275

PARP polyclonal antibody

MBS565256-01mL 0.1mL
EUR 540

PARP polyclonal antibody

MBS565256-5x01mL 5x0.1mL
EUR 2275

Polyclonal PARP Antibody

APR08928G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARP . This antibody is tested and proven to work in the following applications:

PARP-2 Polyclonal Antibody

ABP53414-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-2 Polyclonal Antibody

ABP53414-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-2 Polyclonal Antibody

ABP53414-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-3 Polyclonal Antibody

ABP53415-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-3 Polyclonal Antibody

ABP53415-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-3 Polyclonal Antibody

ABP53415-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-1 Polyclonal Antibody

ABP57383-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

ABP57383-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

ABP57383-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

BT-AP06934-100ul 100ul Ask for price
Description: PARP1 (poly(ADP-ribose) polymerase 1) encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

PARP-1 Polyclonal Antibody

BT-AP06934-20ul 20ul Ask for price
Description: PARP1 (poly(ADP-ribose) polymerase 1) encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

PARP-1 Polyclonal Antibody

BT-AP06934-50ul 50ul Ask for price
Description: PARP1 (poly(ADP-ribose) polymerase 1) encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

PARP-2 Polyclonal Antibody

BT-AP06935-100ul 100ul Ask for price
Description: PARP2 encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. Poly [ADP-ribose] polymerase 2 has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

PARP-2 Polyclonal Antibody

BT-AP06935-20ul 20ul Ask for price
Description: PARP2 encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. Poly [ADP-ribose] polymerase 2 has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

PARP-2 Polyclonal Antibody

BT-AP06935-50ul 50ul Ask for price
Description: PARP2 encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. Poly [ADP-ribose] polymerase 2 has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

PARP-3 Polyclonal Antibody

BT-AP06936-100ul 100ul Ask for price
Description: The poly(ADP-ribose) polymerase family member 3 encoded by PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

PARP-3 Polyclonal Antibody

BT-AP06936-20ul 20ul Ask for price
Description: The poly(ADP-ribose) polymerase family member 3 encoded by PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

PARP-3 Polyclonal Antibody

BT-AP06936-50ul 50ul Ask for price
Description: The poly(ADP-ribose) polymerase family member 3 encoded by PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

PARP-1 Polyclonal Antibody

BT-AP12793-100ul 100ul Ask for price
Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

PARP-1 Polyclonal Antibody

BT-AP12793-20ul 20ul Ask for price
Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

PARP-1 Polyclonal Antibody

BT-AP12793-50ul 50ul Ask for price
Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

PARP-1 Polyclonal Antibody

E11-126210 100ul
EUR 225
Description: Available in various conjugation types.

PARP-1 Polyclonal Antibody

JOT-AP06934-100ul 100ul
EUR 220
Description: Human;Mouse;Rat

PARP-1 Polyclonal Antibody

JOT-AP06934-50ul 50ul
EUR 144
Description: Human;Mouse;Rat

PARP-2 Polyclonal Antibody

JOT-AP06935-100ul 100ul
EUR 220
Description: Human;Mouse

PARP-2 Polyclonal Antibody

JOT-AP06935-50ul 50ul
EUR 144
Description: Human;Mouse

PARP-3 Polyclonal Antibody

JOT-AP06936-100ul 100ul
EUR 220
Description: Human

PARP-3 Polyclonal Antibody

JOT-AP06936-50ul 50ul
EUR 144
Description: Human

PARP-1 Polyclonal Antibody

JOT-AP12793-100ul 100ul
EUR 220

PARP-1 Polyclonal Antibody

JOT-AP12793-50ul 50ul
EUR 144

PARP-2 Polyclonal Antibody

E20-73594 100ug
EUR 225
Description: Available in various conjugation types.

PARP-3 Polyclonal Antibody

E20-73595 100ug
EUR 225
Description: Available in various conjugation types.

PARP-1 Polyclonal Antibody

E20-75695 100ug
EUR 225
Description: Available in various conjugation types.

PARP-2 Polyclonal Antibody

E44H02978 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP-3 Polyclonal Antibody

E44H05802 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP-1 Polyclonal Antibody

E44H07137 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP-1 Polyclonal Antibody

E44H14763 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP-1 polyclonal antibody

MBS566115-01mL 0.1mL
EUR 425

PARP-1 polyclonal antibody

MBS566115-5x01mL 5x0.1mL
EUR 1875

PARP-1 Polyclonal Antibody

MBS2549398-002mL 0.02mL
EUR 140

PARP-1 Polyclonal Antibody

MBS2549398-006mL 0.06mL
EUR 180

PARP-1 Polyclonal Antibody

MBS2549398-012mL 0.12mL
EUR 260

PARP-1 Polyclonal Antibody

MBS2549398-02mL 0.2mL
EUR 405

PARP-1 Polyclonal Antibody

MBS2549398-5x02mL 5x0.2mL
EUR 1725

PARP-2 Polyclonal Antibody

MBS2536940-002mL 0.02mL
EUR 140

PARP-2 Polyclonal Antibody

MBS2536940-006mL 0.06mL
EUR 180

PARP-2 Polyclonal Antibody

MBS2536940-012mL 0.12mL
EUR 260

PARP-2 Polyclonal Antibody

MBS2536940-02mL 0.2mL
EUR 405

PARP-2 Polyclonal Antibody

MBS9244789-01mL 0.1mL
EUR 415

PARP-2 Polyclonal Antibody

MBS9244789-5x01mL 5x0.1mL
EUR 1841

PARP-1 Polyclonal Antibody

MBS9246311-01mL 0.1mL
EUR 415

PARP-1 Polyclonal Antibody

MBS9246311-5x01mL 5x0.1mL
EUR 1841

PARP-1 Polyclonal Antibody

MBS8526676-01mg 0.1mg
EUR 305

PARP-1 Polyclonal Antibody

MBS8526676-01mLAF405L 0.1mL(AF405L)
EUR 465

PARP-1 Polyclonal Antibody

MBS8526676-01mLAF405S 0.1mL(AF405S)
EUR 465

PARP-1 Polyclonal Antibody

MBS8526676-01mLAF610 0.1mL(AF610)
EUR 465

PARP-1 Polyclonal Antibody

MBS8526676-01mLAF635 0.1mL(AF635)
EUR 465

PARP-1 Polyclonal Antibody

MBS8537524-01mL 0.1mL
EUR 305

PARP-1 Polyclonal Antibody

MBS8537524-01mLAF405L 0.1mL(AF405L)
EUR 465

PARP-1 Polyclonal Antibody

MBS8537524-01mLAF405S 0.1mL(AF405S)
EUR 465

PARP-1 Polyclonal Antibody

MBS8537524-01mLAF610 0.1mL(AF610)
EUR 465

PARP-1 Polyclonal Antibody

MBS8537524-01mLAF635 0.1mL(AF635)
EUR 465

PARP-2 Polyclonal Antibody

MBS8524575-01mg 0.1mg
EUR 305

PARP-2 Polyclonal Antibody

MBS8524575-01mLAF405L 0.1mL(AF405L)
EUR 465

PARP-2 Polyclonal Antibody

MBS8524575-01mLAF405S 0.1mL(AF405S)
EUR 465

PARP-2 Polyclonal Antibody

MBS8524575-01mLAF610 0.1mL(AF610)
EUR 465

PARP-2 Polyclonal Antibody

MBS8524575-01mLAF635 0.1mL(AF635)
EUR 465

PARP-3 Polyclonal Antibody

MBS8524576-01mg 0.1mg
EUR 305

PARP-3 Polyclonal Antibody

MBS8524576-01mLAF405L 0.1mL(AF405L)
EUR 465

PARP-3 Polyclonal Antibody

MBS8524576-01mLAF405S 0.1mL(AF405S)
EUR 465

PARP-3 Polyclonal Antibody

MBS8524576-01mLAF610 0.1mL(AF610)
EUR 465

PARP-3 Polyclonal Antibody

MBS8524576-01mLAF635 0.1mL(AF635)
EUR 465

PARP-1 Polyclonal Antibody

UB-GEN-10682 100 ul
EUR 200

PARP-2 Polyclonal Antibody

UB-GEN-472 100 ul
EUR 200

PARP-3 Polyclonal Antibody

UB-GEN-473 100 ul
EUR 200

Cleaved PARP polyclonal antibody

BS90309 50ul
EUR 398
Description: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Mouse polyclonal PARP antibody

MBS5306989-01mg 0.1mg
EUR 550

Mouse polyclonal PARP antibody

MBS5306989-5x01mg 5x0.1mg
EUR 2435

Polyclonal PARP (Cleaved) Antibody

APR08927G 0.1mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARP (Cleaved) . This antibody is tested and proven to work in the following applications:

PARP-1 (D214) polyclonal antibody

BS7047 50ul
EUR 275
Description: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

PARP-2 (mouse) polyclonal antibody

MBS566129-01mL 0.1mL
EUR 465

PARP-2 (mouse) polyclonal antibody

MBS566129-5x01mL 5x0.1mL
EUR 2050

PARP-1 Rabbit Polyclonal Antibody

ES8376-100ul 100ul
EUR 124
Description: WB, ELISA

PARP-1 Rabbit Polyclonal Antibody

ES8376-50ul 50ul
EUR 74
Description: WB, ELISA

PARP-2 Rabbit Polyclonal Antibody

ES4413-100ul 100ul
EUR 124
Description: WB, ELISA

PARP-2 Rabbit Polyclonal Antibody

ES4413-50ul 50ul
EUR 74
Description: WB, ELISA

PARP-3 Rabbit Polyclonal Antibody

ES4414-100ul 100ul
EUR 124
Description: IHC, ELISA

PARP-3 Rabbit Polyclonal Antibody

ES4414-50ul 50ul
EUR 74
Description: IHC, ELISA

PARP (Acetyl-K521) Polyclonal Antibody

HW188 100ul
EUR 319

Polyclonal Cleaved PARP (Asp214) Antibody

APG02631G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cleaved PARP (Asp214) . This antibody is tested and proven to work in the following applications:

Cleaved PARP (Asp214) polyclonal antibody

BS80384 50ul
EUR 358
Description: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Cleaved PARP (Asp214) polyclonal antibody

BS80385 50ul
EUR 358
Description: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Cleaved PARP (Asp214) Polyclonal Antibody

E-AB-93361-120uL 120uL
EUR 320
Description: Unconjugated

Cleaved PARP (Asp214) Polyclonal Antibody

E-AB-93361-200uL 200uL
EUR 530
Description: Unconjugated

Cleaved PARP (Asp214) Polyclonal Antibody

E-AB-93361-60uL 60uL
EUR 200
Description: Unconjugated

Cleaved PARP (Asp214) Polyclonal Antibody

E-AB-93361-each each Ask for price
Description: Unconjugated

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

BT-AP12792-100ul 100ul Ask for price
Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

PARP-1 (Acetyl-K521) Polyclonal Antibody

BT-AP12792-20ul 20ul Ask for price
Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

PARP-1 (Acetyl-K521) Polyclonal Antibody

BT-AP12792-50ul 50ul Ask for price
Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

PARP-1 (Acetyl-K521) Polyclonal Antibody

HW188-100ul 100ul
EUR 302.4

PARP-1 (Acetyl-K521) Polyclonal Antibody

HW188-50ul 50ul
EUR 224.4

PARP-1 (Acetyl-K521) Polyclonal Antibody

E11-2010091 100ug/100ul
EUR 225
Description: Available in various conjugation types.

PARP-1 (Acetyl-K521) Polyclonal Antibody

JOT-AP12792-100ul 100ul
EUR 220

PARP-1 (Acetyl-K521) Polyclonal Antibody

JOT-AP12792-50ul 50ul
EUR 144

PARP-1 (Acetyl-K521) Polyclonal Antibody

E44H00215 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS9241394-01mL 0.1mL
EUR 415

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS9241394-5x01mL 5x0.1mL
EUR 1841

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS8530362-01mg 0.1mg
EUR 305

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS8530362-01mLAF405L 0.1mL(AF405L)
EUR 465

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS8530362-01mLAF405S 0.1mL(AF405S)
EUR 465

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS8530362-01mLAF610 0.1mL(AF610)
EUR 465

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS8530362-01mLAF635 0.1mL(AF635)
EUR 465

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS9428966-005mL 0.05mL
EUR 245

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS9428966-01mL 0.1mL
EUR 305

PARP-1 (Acetyl-K521) Polyclonal Antibody

MBS9428966-5x01mL 5x0.1mL
EUR 1230

PARP-1 (Acetyl-K521) Polyclonal Antibody

UB-GEN-4331 100 ul
EUR 200

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU30228-100ul 100ul
EUR 231.4

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU30228-200ul 200ul
EUR 289

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU28201-100ul 100ul
EUR 217.9

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU28201-200ul 200ul
EUR 272.2

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU28202-100ul 100ul
EUR 212.2

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU28202-200ul 200ul
EUR 265.4

PARP-1 (Acetyl-K521) Rabbit Polyclonal Antibody

ES8828-100ul 100ul
EUR 124
Description: WB, ELISA

PARP-1 (Acetyl-K521) Rabbit Polyclonal Antibody

ES8828-50ul 50ul
EUR 74
Description: WB, ELISA

Myeloid Differentiation Primary Response Gene (88) (MYD88) Rabbit anti-Human Polyclonal (aa233-248) Antibody

GWB-B66568 0.05 mg Ask for price

Myeloid Differentiation Primary Response Gene (88) (MYD88) Rabbit anti-Human Polyclonal (aa233-248) Antibody

GWB-504A56 0.05 mg Ask for price

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat)

4-PAA279Ra01
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  • 20ul
  • 100ul
  • 200ul
  • 1ml
  • 10ml
Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP)

Rabbit polyclonal PARP (Cleaved-Asp214) antibody

TA326295 100 µl Ask for price

Rabbit polyclonal PARP (Cleaved-Gly215) antibody

TA313435 100 µl Ask for price

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human)

4-PAA279Hu01
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  • 20ul
  • 100ul
  • 200ul
  • 1ml
  • 10ml
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP)

Anti-Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

FAA279Mu01 50T
EUR 200

We analyzed the features of the spectrum of gene mutations and mutations signature pattern, and analyzed four pathways altered by mutations of genes in pancreatic neuroendocrine tumors, including DNA damage and repair, chromatin remodeling, maintenance of telomeres and activation of mTOR signaling.