Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).

We conduct exploratory biomarker study of a phase II clinical trial of eribulin plus gemcitabine (EG) versus paclitaxel plus gemcitabine (PG) in metastatic breast cancer HER2-negative (BC) patients.We conducted targeted deep sequencing with adjustable cancer gene panel and RNA expression assay. Tumor mutation load (TMB) and mutation signature is determined based on a genetic change in a targeted area. Gene variation analysis performed by PanCancer set Immune Pathway Profiling and PanCancer Panel. Statistical analysis was performed to identify the relationship between genetic changes and clinical outcomes.Of 119 patients, 40 had a biomarker data available.

Among the 40 patients, 4 post-treatment network support them. In targeted sequencing in, FAT3 (48%) is the most frequently mutated gene, followed by PKHD1, TP53, GATA3, PARP4, and PIK3CA. In terms of gene expression, low expression of epithelial-mesenchymal transition (EMT) pathway genes associated with prolonged progression-free survival (PFS) in the group EG, while high expression of EMT pathway is associated with a good prognosis in the PG group. TMB median was 6.5 (range 2.44 to 46.34) and no association between TMB and the patient’s prognosis.

Signature mutation analysis showed that the signature of 3, 20, and 26 which are often observed in our group. Survival analysis Furthermore, according to the signature mutations shows that mutations signature 3, as signature-related deficiencies homologous recombinant, it is strongly associated with disease progression (hazard ratio (log2 scale) 8:21, the 95% confidence interval 2.93 to 13.48 , p = 0.002).

Kaplan-Meier plot also shows that the BCs with signature 3 has a shorter PFS compared with those who did not sign this (median PFS (months) for signing 3 (low vs. high): 17.2 vs. 8.1, p = 0, 0026) .Mutation signature 3, found in about 30% of MBCS regardless of hormone receptor status, was associated with shorter PFS for patients with cytotoxic chemotherapy.

Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).
Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).

Modifications PARP4, XRCC3, and RAD51 Gene Polymorphism on the relationship between Bisphenol A Exposure and liver abnormalities.

repair genes may play an important role in the relationship between environmental exposures and health outcomes. However, no evidence was available about the effect of genetic polymorphisms on the improvement of the relationship between bisphenol A (BPA) exposure and liver abnormalities.

Therefore, we evaluated the effect of nine polymorphism genotypes in three genes repair, poly (ADP-ribose) member polymerase family of 4 (PARP4), X-ray repair cross-complementary 3 (XRCC3), and RAD51 recombinase (RAD51), in relation between exposure to BPA and heart abnormalities using repeated measures of data for the elderly population.

A significant association between BPA levels and liver abnormalities are found only in elders with PARP4 haplotype GCG, XRCC3 GAG haplotype, or RAD51 TAA haplotype (odds ratio (OR) = 2.16 and p = 0.0014 for PARP4; OR = 1.57 and p = 0.0249 for XRCC3; OR = 1.43 and p = 0.0422 for RAD51). Especially, PARP4 and XRCC3 showed significant interaction with BPA exposure in relation to liver abnormalities (p <0.05 for both genes). These results indicate that PARP4, XRCC3, and RAD51 gene polymorphism has the effect of modifications on the relationship between exposure to BPA and heart abnormalities.

Colorectal neuroendocrine tumors (nets) are rare neoplasms and study of colorectal nets is relatively small compared with other tumors. To better understand the pathogenesis of this tumor, we performed whole genome sequencing and follow-up verification using Sanger sequencing of colorectal and paired Nets para-tumor tissue.

PARP-2 Polyclonal Antibody

ABP53414-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-2 Polyclonal Antibody

ABP53414-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-3 Polyclonal Antibody

ABP53415-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-3 Polyclonal Antibody

ABP53415-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-3 Polyclonal Antibody

ABP53415-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-1 Polyclonal Antibody

ABP57383-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

ABP57383-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

ABP57383-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

E11-126210 100ul
EUR 225
Description: Available in various conjugation types.

PARP-1 Polyclonal Antibody

E20-75695 100ug
EUR 225
Description: Available in various conjugation types.

PARP-2 Polyclonal Antibody

E20-73594 100ug
EUR 225
Description: Available in various conjugation types.

PARP-3 Polyclonal Antibody

E20-73595 100ug
EUR 225
Description: Available in various conjugation types.

PARP-3 Polyclonal Antibody

E44H05802 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP-1 Polyclonal Antibody

E44H07137 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP-2 Polyclonal Antibody

E44H02978 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP-1 Polyclonal Antibody

E44H14763 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Polyclonal PARP Antibody

APR08928G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARP . This antibody is tested and proven to work in the following applications:

PARP-1 Rabbit Polyclonal Antibody

ES8376-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against PARP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-1 Rabbit Polyclonal Antibody

ES8376-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against PARP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-2 Rabbit Polyclonal Antibody

ES4413-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against PARP-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-2 Rabbit Polyclonal Antibody

ES4413-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against PARP-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-3 Rabbit Polyclonal Antibody

ES4414-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against PARP-3 from Human. This antibody is tested and validated for IHC, WB, ELISA

PARP-3 Rabbit Polyclonal Antibody

ES4414-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against PARP-3 from Human. This antibody is tested and validated for IHC, WB, ELISA

Polyclonal PARP (Cleaved) Antibody

APR08927G 0.1mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARP (Cleaved) . This antibody is tested and proven to work in the following applications:

PARP (Acetyl-K521) Polyclonal Antibody

HW188 100ul
EUR 319

Cleaved PARP (Asp214) Polyclonal Antibody

E-AB-93361-120uL 120uL
EUR 320
Description: Unconjugated

Cleaved PARP (Asp214) Polyclonal Antibody

E-AB-93361-200uL 200uL
EUR 530
Description: Unconjugated

Cleaved PARP (Asp214) Polyclonal Antibody

E-AB-93361-60uL 60uL
EUR 200
Description: Unconjugated

Cleaved PARP (Asp214) Polyclonal Antibody

E-AB-93361-each each Ask for price
Description: Unconjugated

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

E11-2010091 100ug/100ul
EUR 225
Description: Available in various conjugation types.

PARP-1 (Acetyl-K521) Polyclonal Antibody

HW188-100ul 100ul
EUR 302.4

PARP-1 (Acetyl-K521) Polyclonal Antibody

HW188-50ul 50ul
EUR 224.4

PARP-1 (Acetyl-K521) Polyclonal Antibody

E44H00215 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Polyclonal Cleaved PARP (Asp214) Antibody

APG02631G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cleaved PARP (Asp214) . This antibody is tested and proven to work in the following applications:

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU28201-100ul 100ul
EUR 217.9

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU28201-200ul 200ul
EUR 272.2

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU28202-100ul 100ul
EUR 212.2

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU28202-200ul 200ul
EUR 265.4

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU30228-100ul 100ul
EUR 231.4

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

CAU30228-200ul 200ul
EUR 289

PARP-1 (Acetyl-K521) Rabbit Polyclonal Antibody

ES8828-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against PARP-1 (Acetyl-K521) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-1 (Acetyl-K521) Rabbit Polyclonal Antibody

ES8828-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against PARP-1 (Acetyl-K521) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat)

4-PAA279Ra01
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  • 100ul
  • 10ml
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Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP)

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human)

4-PAA279Hu01
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP)

Anti-Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody

FAA279Mu01 50T
EUR 200

Rabbit polyclonal PARP (Cleaved-Gly215) antibody

TA313435 100 µl Ask for price

Rabbit polyclonal PARP (Cleaved-Asp214) antibody

TA326295 100 µl Ask for price

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat), PE

4-PAA279Ra01-PE
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  • 100ul
  • 10ml
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Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP). This antibody is labeled with PE.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat), APC

4-PAA279Ra01-APC
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  • 100ul
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Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP). This antibody is labeled with APC.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat), Cy3

4-PAA279Ra01-Cy3
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  • 100ul
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Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP). This antibody is labeled with Cy3.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat), HRP

4-PAA279Ra01-HRP
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  • 100ul
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Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP). This antibody is labeled with HRP.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human), PE

4-PAA279Hu01-PE
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP). This antibody is labeled with PE.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat), FITC

4-PAA279Ra01-FITC
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  • 100ul
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Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP). This antibody is labeled with FITC.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human), APC

4-PAA279Hu01-APC
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP). This antibody is labeled with APC.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human), Cy3

4-PAA279Hu01-Cy3
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP). This antibody is labeled with Cy3.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human), HRP

4-PAA279Hu01-HRP
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP). This antibody is labeled with HRP.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human), FITC

4-PAA279Hu01-FITC
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP). This antibody is labeled with FITC.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human, Mouse)

4-PAA279Mu01
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human, Mouse Poly ADP Ribose Polymerase (PARP)

Polyclonal Antibody to Poly ADP Ribose Polymerase (PARP)

PAA279Hu01 100ul
EUR 221

Polyclonal Antibody to Poly ADP Ribose Polymerase (PARP)

PAA279Mu01 100ul
EUR 227

Polyclonal Antibody to Poly ADP Ribose Polymerase (PARP)

PAA279Ra01 100ul
EUR 241

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat), Biotinylated

4-PAA279Ra01-Biotin
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  • 100ul
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Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP). This antibody is labeled with Biotin.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human), Biotinylated

4-PAA279Hu01-Biotin
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Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP). This antibody is labeled with Biotin.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat), APC-Cy7

4-PAA279Ra01-APC-Cy7
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Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP). This antibody is labeled with APC-Cy7.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human, Mouse), PE

4-PAA279Mu01-PE
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human, Mouse Poly ADP Ribose Polymerase (PARP). This antibody is labeled with PE.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human), APC-Cy7

4-PAA279Hu01-APC-Cy7
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP). This antibody is labeled with APC-Cy7.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human, Mouse), APC

4-PAA279Mu01-APC
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Description: A Rabbit polyclonal antibody against Human, Mouse Poly ADP Ribose Polymerase (PARP). This antibody is labeled with APC.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human, Mouse), Cy3

4-PAA279Mu01-Cy3
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Description: A Rabbit polyclonal antibody against Human, Mouse Poly ADP Ribose Polymerase (PARP). This antibody is labeled with Cy3.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human, Mouse), HRP

4-PAA279Mu01-HRP
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Description: A Rabbit polyclonal antibody against Human, Mouse Poly ADP Ribose Polymerase (PARP). This antibody is labeled with HRP.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human, Mouse), FITC

4-PAA279Mu01-FITC
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Description: A Rabbit polyclonal antibody against Human, Mouse Poly ADP Ribose Polymerase (PARP). This antibody is labeled with FITC.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human, Mouse), Biotinylated

4-PAA279Mu01-Biotin
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Description: A Rabbit polyclonal antibody against Human, Mouse Poly ADP Ribose Polymerase (PARP). This antibody is labeled with Biotin.

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human, Mouse), APC-Cy7

4-PAA279Mu01-APC-Cy7
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Description: A Rabbit polyclonal antibody against Human, Mouse Poly ADP Ribose Polymerase (PARP). This antibody is labeled with APC-Cy7.

Cleaved-PARP (G215) Polyclonal Antibody

40519 100ul
EUR 319

Rabbit Polyclonal Cleaved-PARP antibody

TA325762 100 µl Ask for price

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP0027-100uL 100 μL
EUR 229
Description: Rabbit Anti-Cleaved-PARP-1 (D214) Polyclonal Antibody

Cleaved-PARP-1 (G215) Polyclonal Antibody

ABP50053-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250

Cleaved-PARP-1 (G215) Polyclonal Antibody

ABP50053-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250

Cleaved-PARP-1 (G215) Polyclonal Antibody

ABP50053-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP50072-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP50072-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP50072-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220

Cleaved-PARP-1 (G215) Polyclonal Antibody

40519-100ul 100ul
EUR 302.4

Cleaved-PARP-1 (G215) Polyclonal Antibody

40519-50ul 50ul
EUR 224.4

Cleaved-PARP-1 (D214) Polyclonal Antibody

40520-100ul 100ul
EUR 302.4

Cleaved-PARP-1 (D214) Polyclonal Antibody

40520-50ul 50ul
EUR 224.4

Cleaved-PARP-1 (G215) Polyclonal Antibody

E040519 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Cleaved-PARP-1 (D214) Polyclonal Antibody

E040520 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Cleaved-PARP-1 (G215) Polyclonal Antibody

E20-10073 100ug
EUR 225
Description: Available in various conjugation types.

Cleaved-PARP-1 (D214) Polyclonal Antibody

E20-10101 100ug
EUR 225
Description: Available in various conjugation types.

Cleaved-PARP-1 (G215) Polyclonal Antibody

E44H00073 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Cleaved-PARP-1 (D214) Polyclonal Antibody

E44H00101 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP0027-each each Ask for price

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP0027-Null Null Ask for price

Cleaved-PARP-1 (G215) Rabbit Polyclonal Antibody

ES1052-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (G215) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cleaved-PARP-1 (G215) Rabbit Polyclonal Antibody

ES1052-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (G215) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cleaved-PARP-1 (D214) Rabbit Polyclonal Antibody

ES1071-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (D214) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Cleaved-PARP-1 (D214) Rabbit Polyclonal Antibody

ES1071-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (D214) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody

CAU23692-100ul 100ul
EUR 235.2

Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody

CAU23692-200ul 200ul
EUR 294

PARP12 Polyclonal Antibody

28501 100ul
EUR 439

PARP12 Polyclonal Antibody

28501-100ul 100ul
EUR 302.4

PARP12 Polyclonal Antibody

28501-50ul 50ul
EUR 224.4

PARP12 Polyclonal Antibody

E914317 100ul
EUR 225
Description: Available in various conjugation types.

PARP10 Polyclonal Antibody

E-AB-13492-120uL 120uL
EUR 240
Description: Unconjugated

PARP10 Polyclonal Antibody

E-AB-13492-200uL 200uL
EUR 399
Description: Unconjugated

PARP10 Polyclonal Antibody

E-AB-13492-20uL 20uL
EUR 73
Description: Unconjugated

PARP10 Polyclonal Antibody

E-AB-13492-60uL 60uL
EUR 143
Description: Unconjugated

PARP11 Polyclonal Antibody

E-AB-11474-120uL 120uL
EUR 240
Description: Unconjugated

PARP11 Polyclonal Antibody

E-AB-11474-200uL 200uL
EUR 399
Description: Unconjugated

PARP11 Polyclonal Antibody

E-AB-11474-20uL 20uL
EUR 73
Description: Unconjugated

PARP11 Polyclonal Antibody

E-AB-11474-60uL 60uL
EUR 143
Description: Unconjugated

PARP10 Polyclonal Antibody

E-AB-64335-120uL 120uL
EUR 320
Description: Unconjugated

PARP10 Polyclonal Antibody

E-AB-64335-200uL 200uL
EUR 530
Description: Unconjugated

PARP10 Polyclonal Antibody

E-AB-64335-60uL 60uL
EUR 200
Description: Unconjugated

PARP10 Polyclonal Antibody

E-AB-64335-each each Ask for price
Description: Unconjugated

PARP6 Polyclonal Antibody

ABP59833-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP6 from Human, Mouse. This PARP6 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP6 protein

PARP6 Polyclonal Antibody

ABP59833-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP6 from Human, Mouse. This PARP6 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP6 protein

PARP6 Polyclonal Antibody

ABP59833-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP6 from Human, Mouse. This PARP6 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP6 protein

PARP8 Polyclonal Antibody

ABP59834-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP8 from Human, Mouse. This PARP8 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP8 protein at amino acid sequence of 60-140

PARP8 Polyclonal Antibody

ABP59834-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP8 from Human, Mouse. This PARP8 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP8 protein at amino acid sequence of 60-140

PARP8 Polyclonal Antibody

ABP59834-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP8 from Human, Mouse. This PARP8 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP8 protein at amino acid sequence of 60-140

PARP9 Polyclonal Antibody

ABP59835-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP9 from Human, Mouse. This PARP9 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP9 protein at amino acid sequence of 450-530

PARP9 Polyclonal Antibody

ABP59835-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP9 from Human, Mouse. This PARP9 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP9 protein at amino acid sequence of 450-530

PARP9 Polyclonal Antibody

ABP59835-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP9 from Human, Mouse. This PARP9 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP9 protein at amino acid sequence of 450-530

PARP9 Polyclonal Antibody

29322 100ul
EUR 439

PARP9 Polyclonal Antibody

29322-100ul 100ul
EUR 302.4

PARP9 Polyclonal Antibody

29322-50ul 50ul
EUR 224.4

PARP8 Polyclonal Antibody

E11-201069 100ug/100ul
EUR 225
Description: Available in various conjugation types.

PARP6 Polyclonal Antibody

E11-202014 100ug/100ul
EUR 225
Description: Available in various conjugation types.

PARP9 Polyclonal Antibody

E11-202328 100ug/100ul
EUR 225
Description: Available in various conjugation types.

PARP1 Polyclonal Antibody

E90010a 100ul
EUR 225
Description: Available in various conjugation types.

PARP1 Polyclonal Antibody

E90942 100ul
EUR 225
Description: Available in various conjugation types.

PARP1 Polyclonal Antibody

E911010 100ul
EUR 225
Description: Available in various conjugation types.

PARP2 Polyclonal Antibody

E916475 100ul
EUR 225
Description: Available in various conjugation types.

PARP4 Polyclonal Antibody

E916749 100ul
EUR 225
Description: Available in various conjugation types.

PARP9 Polyclonal Antibody

E915526 100ul
EUR 225
Description: Available in various conjugation types.

PARP8 Polyclonal Antibody

E44H08676 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP6 Polyclonal Antibody

E44H09621 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP9 Polyclonal Antibody

E44H09935 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PARP1 Polyclonal Antibody

A73231 50 μl
EUR 557

PARP4 Polyclonal Antibody

E-AB-91627-120uL 120uL
EUR 320
Description: Unconjugated

PARP4 Polyclonal Antibody

E-AB-91627-200uL 200uL
EUR 530
Description: Unconjugated

PARP4 Polyclonal Antibody

E-AB-91627-60uL 60uL
EUR 200
Description: Unconjugated

PARP4 Polyclonal Antibody

E-AB-91627-each each Ask for price
Description: Unconjugated

PARP1 Polyclonal Antibody

E-AB-12834-120uL 120uL
EUR 240
Description: Unconjugated

PARP1 Polyclonal Antibody

E-AB-12834-200uL 200uL
EUR 399
Description: Unconjugated

PARP1 Polyclonal Antibody

E-AB-12834-20uL 20uL
EUR 73
Description: Unconjugated

PARP1 Polyclonal Antibody

E-AB-12834-60uL 60uL
EUR 143
Description: Unconjugated

We analyzed the features of the spectrum of gene mutations and mutations signature pattern, and analyzed four pathways altered by mutations of genes in pancreatic neuroendocrine tumors, including DNA damage and repair, chromatin remodeling, maintenance of telomeres and activation of mTOR signaling.