Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).

We conduct exploratory biomarker study of a phase II clinical trial of eribulin plus gemcitabine (EG) versus paclitaxel plus gemcitabine (PG) in metastatic breast cancer HER2-negative (BC) patients.We conducted targeted deep sequencing with adjustable cancer gene panel and RNA expression assay. Tumor mutation load (TMB) and mutation signature is determined based on a genetic change in a targeted area. Gene variation analysis performed by PanCancer set Immune Pathway Profiling and PanCancer Panel. Statistical analysis was performed to identify the relationship between genetic changes and clinical outcomes.Of 119 patients, 40 had a biomarker data available.

Among the 40 patients, 4 post-treatment network support them. In targeted sequencing in, FAT3 (48%) is the most frequently mutated gene, followed by PKHD1, TP53, GATA3, PARP4, and PIK3CA. In terms of gene expression, low expression of epithelial-mesenchymal transition (EMT) pathway genes associated with prolonged progression-free survival (PFS) in the group EG, while high expression of EMT pathway is associated with a good prognosis in the PG group. TMB median was 6.5 (range 2.44 to 46.34) and no association between TMB and the patient’s prognosis.

Signature mutation analysis showed that the signature of 3, 20, and 26 which are often observed in our group. Survival analysis Furthermore, according to the signature mutations shows that mutations signature 3, as signature-related deficiencies homologous recombinant, it is strongly associated with disease progression (hazard ratio (log2 scale) 8:21, the 95% confidence interval 2.93 to 13.48 , p = 0.002).

Kaplan-Meier plot also shows that the BCs with signature 3 has a shorter PFS compared with those who did not sign this (median PFS (months) for signing 3 (low vs. high): 17.2 vs. 8.1, p = 0, 0026) .Mutation signature 3, found in about 30% of MBCS regardless of hormone receptor status, was associated with shorter PFS for patients with cytotoxic chemotherapy.

Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).
Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).

Modifications PARP4, XRCC3, and RAD51 Gene Polymorphism on the relationship between Bisphenol A Exposure and liver abnormalities.

repair genes may play an important role in the relationship between environmental exposures and health outcomes. However, no evidence was available about the effect of genetic polymorphisms on the improvement of the relationship between bisphenol A (BPA) exposure and liver abnormalities.

Therefore, we evaluated the effect of nine polymorphism genotypes in three genes repair, poly (ADP-ribose) member polymerase family of 4 (PARP4), X-ray repair cross-complementary 3 (XRCC3), and RAD51 recombinase (RAD51), in relation between exposure to BPA and heart abnormalities using repeated measures of data for the elderly population.

A significant association between BPA levels and liver abnormalities are found only in elders with PARP4 haplotype GCG, XRCC3 GAG haplotype, or RAD51 TAA haplotype (odds ratio (OR) = 2.16 and p = 0.0014 for PARP4; OR = 1.57 and p = 0.0249 for XRCC3; OR = 1.43 and p = 0.0422 for RAD51). Especially, PARP4 and XRCC3 showed significant interaction with BPA exposure in relation to liver abnormalities (p <0.05 for both genes). These results indicate that PARP4, XRCC3, and RAD51 gene polymorphism has the effect of modifications on the relationship between exposure to BPA and heart abnormalities.

Colorectal neuroendocrine tumors (nets) are rare neoplasms and study of colorectal nets is relatively small compared with other tumors. To better understand the pathogenesis of this tumor, we performed whole genome sequencing and follow-up verification using Sanger sequencing of colorectal and paired Nets para-tumor tissue.

PARP-2 Polyclonal Antibody

ABP53414-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-2 Polyclonal Antibody

ABP53414-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-3 Polyclonal Antibody

ABP53415-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-3 Polyclonal Antibody

ABP53415-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-3 Polyclonal Antibody

ABP53415-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-1 Polyclonal Antibody

ABP57383-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

ABP57383-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

ABP57383-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

Polyclonal PARP (Cleaved) Antibody

APR08927G 0.1mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARP (Cleaved) . This antibody is tested and proven to work in the following applications:

PARP-2 Polyclonal Antibody

ES4413-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against PARP-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-2 Polyclonal Antibody

ES4413-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against PARP-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-3 Polyclonal Antibody

ES4414-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against PARP-3 from Human. This antibody is tested and validated for IHC, WB, ELISA

PARP-3 Polyclonal Antibody

ES4414-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against PARP-3 from Human. This antibody is tested and validated for IHC, WB, ELISA

PARP-1 Polyclonal Antibody

ES8376-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against PARP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-1 Polyclonal Antibody

ES8376-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against PARP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

DLR-PARP-Hu-48T 48T
EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Poly ADP Ribose Polymerase (PARP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

DLR-PARP-Hu-96T 96T
EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Poly ADP Ribose Polymerase (PARP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

DLR-PARP-Mu-48T 48T
EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Poly ADP Ribose Polymerase (PARP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

DLR-PARP-Mu-96T 96T
EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Poly ADP Ribose Polymerase (PARP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

RD-PARP-Hu-48Tests 48 Tests
EUR 573.6

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

RD-PARP-Hu-96Tests 96 Tests
EUR 794.4

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

RD-PARP-Mu-48Tests 48 Tests
EUR 639.6

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

RD-PARP-Mu-96Tests 96 Tests
EUR 888

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

RDR-PARP-Hu-48Tests 48 Tests
EUR 600

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

RDR-PARP-Hu-96Tests 96 Tests
EUR 830.4

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

RDR-PARP-Mu-48Tests 48 Tests
EUR 668.4

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

RDR-PARP-Mu-96Tests 96 Tests
EUR 928.8

PARP antibody

70R-11555 100 ug
EUR 484.8
Description: Rabbit polyclonal PARP antibody

PARP antibody

70R-11640 100 ug
EUR 733.2
Description: Rabbit polyclonal PARP antibody

PARP antibody

70R-11641 100 ug
EUR 697.2
Description: Rabbit polyclonal PARP antibody

PARP antibody

70R-30801 100 ug
EUR 392.4
Description: Rabbit polyclonal PARP antibody

PARP antibody

70R-30803 100 ug
EUR 392.4
Description: Rabbit polyclonal PARP antibody

PARP Antibody

48838-100ul 100ul
EUR 399.6

PARP Antibody

48838-50ul 50ul
EUR 286.8

PARP antibody

10R-8001 100 ul
EUR 603.6
Description: Mouse monoclonal PARP antibody

PARP antibody

10R-8057 100 ug
EUR 564
Description: Mouse polyclonal PARP antibody

PARP antibody

20R-1423 100 ug
EUR 807.6
Description: Rabbit polyclonal PARP antibody

PARP antibody

10R-2170 100 ul
EUR 483.6
Description: Mouse monoclonal PARP antibody

PARP Antibody

3002-100
EUR 379.2

PARP Antibody

3002-30T
EUR 175.2

PARP antibody

BF0719 200ul
EUR 540

PARP Antibody

R31722 100 ug
EUR 419

PARP Antibody

F49614-0.08ML 0.08 ml
EUR 165

PARP Antibody

F49614-0.4ML 0.4 ml
EUR 379

PARP Antibody

F47592-0.08ML 0.08 ml
EUR 165

PARP Antibody

F47598-0.08ML 0.08 ml
EUR 165

Polyclonal Cleaved PARP (Asp214) Antibody

APG02631G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cleaved PARP (Asp214) . This antibody is tested and proven to work in the following applications:

Cleaved-PARP-1 (G215) Polyclonal Antibody

40519-100ul 100ul
EUR 302.4

Cleaved-PARP-1 (G215) Polyclonal Antibody

40519-50ul 50ul
EUR 224.4

Cleaved-PARP-1 (D214) Polyclonal Antibody

40520-100ul 100ul
EUR 302.4

Cleaved-PARP-1 (D214) Polyclonal Antibody

40520-50ul 50ul
EUR 224.4

Cleaved-PARP-1 (G215) Polyclonal Antibody

ABP50053-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250

Cleaved-PARP-1 (G215) Polyclonal Antibody

ABP50053-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250

Cleaved-PARP-1 (G215) Polyclonal Antibody

ABP50053-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP50072-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP50072-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP50072-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

Cleaved-PARP-1 (G215) Polyclonal Antibody

ES1052-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (G215) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cleaved-PARP-1 (G215) Polyclonal Antibody

ES1052-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (G215) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cleaved-PARP-1 (D214) Polyclonal Antibody

ES1071-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (D214) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Cleaved-PARP-1 (D214) Polyclonal Antibody

ES1071-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (D214) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

PARP-1 (Acetyl-K521) Polyclonal Antibody

ES8828-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against PARP-1 (Acetyl-K521) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-1 (Acetyl-K521) Polyclonal Antibody

ES8828-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against PARP-1 (Acetyl-K521) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-1 (Acetyl-K521) Polyclonal Antibody

HW188-100ul 100ul
EUR 302.4

PARP-1 (Acetyl-K521) Polyclonal Antibody

HW188-50ul 50ul
EUR 224.4

Cleaved PARP Antibody

48805-100ul 100ul
EUR 399.6

Cleaved PARP Antibody

48805-50ul 50ul
EUR 286.8

PARP (Cleaved) Antibody

3140-100
EUR 561.6

PARP (Cleaved) Antibody

3141-100
EUR 535.2

Cleaved-PARP antibody

29033-100ul 100ul
EUR 302.4

Cleaved PARP Antibody

abx020094-100ug 100 ug
EUR 526.8

Cleaved- PARP antibody

ABF7023 100 ug
EUR 525.6

PARP Monoclonal Antibody

ABM40131-003ml 0.03ml
EUR 189.6
Description: A monoclonal antibody for detection of PARP from Human. This PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

PARP Monoclonal Antibody

ABM40131-01ml 0.1ml
EUR 346.8
Description: A monoclonal antibody for detection of PARP from Human. This PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

PARP Monoclonal Antibody

ABM40131-02ml 0.2ml
EUR 496.8
Description: A monoclonal antibody for detection of PARP from Human. This PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved-PARP Antibody

BF9106 200ul
EUR 540

PARP Monoclonal Antibody

EM1131-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

PARP Monoclonal Antibody

EM1131-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Anti-PARP antibody

STJ97033 200 µl
EUR 236.4
Description: Mouse monoclonal to PARP.

PARP 1 Antibody

F47598-0.4ML 0.4 ml
EUR 379

PARP/ Rat PARP ELISA Kit

ELA-E0947r 96 Tests
EUR 1063.2

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human)

4-PAA279Hu01
  • EUR 278.40
  • EUR 2742.00
  • EUR 688.80
  • EUR 346.80
  • EUR 249.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP)

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat)

4-PAA279Ra01
  • EUR 292.80
  • EUR 2964.00
  • EUR 739.20
  • EUR 367.20
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP)

IL-4 Interleukin 4 Human Recombinant Protein, Yeast

PROTP05112-4 Regular: 10ug
EUR 380.4
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

Cleaved-PARP-1 (D214) Polyclonal Conjugated Antibody

C40520 100ul
EUR 476.4

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human, Mouse)

4-PAA279Mu01
  • EUR 283.20
  • EUR 2805.60
  • EUR 703.20
  • EUR 352.80
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Poly ADP Ribose Polymerase (PARP)

PARP Antibody (Clone 839120)

6659-100
EUR 483.6

Anti-PARP-2 Antibody

A03270-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for PARP-2 Antibody (PARP2) detection. Tested with WB in Human, Mouse.

Anti-PARP-3 Antibody

A03762 100ul
EUR 626.4
Description: Rabbit Polyclonal PARP-3 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse.

PARP Antibody (Clone 2B6)

A1109-100
EUR 430.8

Human PARP-2 Antibody

32035-05111 150 ug
EUR 313.2

PARP Antibody (Clone 7A10)

3023-100
EUR 483.6

PARP Mouse Monoclonal Antibody

38067-100ul 100ul
EUR 302.4

PARP Mouse Monoclonal Antibody

38067-50ul 50ul
EUR 224.4

PARP Antibody (Clone 10H)

3000-100
EUR 444

PARP (Cleaved-Asp214) Antibody

20-abx015613
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

PARP (Cleaved-Gly215) Antibody

20-abx015614
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

PARP recombinant monoclonal antibody

A5037 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human PARP for WB,ELISA

Cleaved PARP Monoclonal Antibody

ABM40132-003ml 0.03ml
EUR 189.6
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40132-01ml 0.1ml
EUR 346.8
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40132-02ml 0.2ml
EUR 496.8
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40145-003ml 0.03ml
EUR 189.6
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40145-01ml 0.1ml
EUR 346.8
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40145-02ml 0.2ml
EUR 496.8
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Anti-PARP-1 Antibody

A00122-1 100ul
EUR 476.4
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.

Cleaved-PARP (Asp214) Antibody

AF7023 200ul
EUR 540

PARP antibody Blocking Peptide

BF0719-BP 1mg
EUR 234

Cleaved-PARP Conjugated Antibody

C29033 100ul
EUR 476.4

Cleaved PARP Monoclonal Antibody

EM1132-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against Cleaved PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Cleaved PARP Monoclonal Antibody

EM1132-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against Cleaved PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Cleaved PARP Monoclonal Antibody

EM1145-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against Cleaved PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Cleaved PARP Monoclonal Antibody

EM1145-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against Cleaved PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Anti-PARP/PARP1 Antibody

PA2227 100ug/vial
EUR 352.8

Anti-PARP/PARP1 Antibody

PB9309 100ug/vial
EUR 400.8

Monoclonal antibody for PARP

SMC-259D 0.1ml
EUR 376.8
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is not conjugated.

Monoclonal antibody for PARP

SMC-259D-A390 0.1ml
EUR 433.2
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 390.

Monoclonal antibody for PARP

SMC-259D-A488 0.1ml
EUR 432
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 488.

Monoclonal antibody for PARP

SMC-259D-A565 0.1ml
EUR 432
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 565.

Monoclonal antibody for PARP

SMC-259D-A594 0.1ml
EUR 432
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 594.

Monoclonal antibody for PARP

SMC-259D-A633 0.1ml
EUR 432
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 633.

Monoclonal antibody for PARP

SMC-259D-A655 0.1ml
EUR 432
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 655.

Monoclonal antibody for PARP

SMC-259D-A680 0.1ml
EUR 432
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 680.

Monoclonal antibody for PARP

SMC-259D-A700 0.1ml
EUR 432
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 700.

Monoclonal antibody for PARP

SMC-259D-ALP 0.1ml
EUR 426
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Alkaline Phosphatase.

Monoclonal antibody for PARP

SMC-259D-APC 0.1ml
EUR 430.8
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with APC.

Monoclonal antibody for PARP

SMC-259D-APCCY7 0.1ml
EUR 518.4
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with APC/Cy7.

Monoclonal antibody for PARP

SMC-259D-BI 0.1ml
EUR 428.4
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Biotin.

Monoclonal antibody for PARP

SMC-259D-DY350 0.1ml
EUR 523.2
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 350.

Monoclonal antibody for PARP

SMC-259D-DY405 0.1ml
EUR 494.4
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 405.

Monoclonal antibody for PARP

SMC-259D-DY488 0.1ml
EUR 471.6
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 488.

Monoclonal antibody for PARP

SMC-259D-DY594 0.1ml
EUR 476.4
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 594.

Monoclonal antibody for PARP

SMC-259D-DY633 0.1ml
EUR 464.4
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 633.

Monoclonal antibody for PARP

SMC-259D-FITC 0.1ml
EUR 423.6
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with FITC.

Monoclonal antibody for PARP

SMC-259D-HRP 0.1ml
EUR 418.8
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with HRP.

Monoclonal antibody for PARP

SMC-259D-P594 0.1ml
EUR 440.4
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with PE/ATTO 594.

Monoclonal antibody for PARP

SMC-259D-PCP 0.1ml
EUR 430.8
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with PerCP.

Monoclonal antibody for PARP

SMC-259D-RPE 0.1ml
EUR 429.6
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with RPE.

Monoclonal antibody for PARP

SMC-259D-STR 0.1ml
EUR 430.8
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Streptavidin.

Anti-PARP-2 antibody

STJ94959 200 µl
EUR 236.4
Description: Rabbit polyclonal to PARP-2.

Anti-PARP-3 antibody

STJ94960 200 µl
EUR 236.4
Description: Rabbit polyclonal to PARP-3.

Anti-Cleaved PARP antibody

STJ97034 200 µl
EUR 236.4
Description: Mouse monoclonal to Cleaved PARP.

Anti-Cleaved PARP antibody

STJ97047 200 µl
EUR 236.4
Description: Cleaved-PARP-1 is a protein encoded by the PARP1 gene which is approximately 113 kDa. Cleaved-PARP-1 is localised to the nucleus. It is involved in telomere C-strand synthesis, transcription-coupled nucleotide excision repair and survival caspase cascades. It is a chromatin-associated enzyme, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is DNA dependent and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation. It also pays a role in the regulation of the molecular events involved in the recovery of cell from DNA damage. Cleaved-PARP-1 is expressed in the nervous system, liver, intestine, lung and eye. Mutations in the PARP1 gene may result in diphtheria and hemorrhagic cystitis. The antibody STJ97047 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels Cleaved-PARP-1.

Anti-PARP-1 antibody

STJ97648 200 µl
EUR 236.4
Description: Rabbit polyclonal to PARP-1.

PARP Antibody (phospho-S177)

F48726-0.08ML 0.08 ml
EUR 165

Phospho-PARP Antibody (pS177)

F48726-0.4ML 0.4 ml
EUR 379

PARP Antibody (phospho-S372)

F48728-0.08ML 0.08 ml
EUR 165

p-PARP Antibody (pS372)

F48728-0.4ML 0.4 ml
EUR 379

PARP Antibody (phospho-S41)

F48729-0.08ML 0.08 ml
EUR 165

We analyzed the features of the spectrum of gene mutations and mutations signature pattern, and analyzed four pathways altered by mutations of genes in pancreatic neuroendocrine tumors, including DNA damage and repair, chromatin remodeling, maintenance of telomeres and activation of mTOR signaling.