Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).

We conduct exploratory biomarker study of a phase II clinical trial of eribulin plus gemcitabine (EG) versus paclitaxel plus gemcitabine (PG) in metastatic breast cancer HER2-negative (BC) patients.We conducted targeted deep sequencing with adjustable cancer gene panel and RNA expression assay. Tumor mutation load (TMB) and mutation signature is determined based on a genetic change in a targeted area. Gene variation analysis performed by PanCancer set Immune Pathway Profiling and PanCancer Panel. Statistical analysis was performed to identify the relationship between genetic changes and clinical outcomes.Of 119 patients, 40 had a biomarker data available.

Among the 40 patients, 4 post-treatment network support them. In targeted sequencing in, FAT3 (48%) is the most frequently mutated gene, followed by PKHD1, TP53, GATA3, PARP4, and PIK3CA. In terms of gene expression, low expression of epithelial-mesenchymal transition (EMT) pathway genes associated with prolonged progression-free survival (PFS) in the group EG, while high expression of EMT pathway is associated with a good prognosis in the PG group. TMB median was 6.5 (range 2.44 to 46.34) and no association between TMB and the patient’s prognosis.

Signature mutation analysis showed that the signature of 3, 20, and 26 which are often observed in our group. Survival analysis Furthermore, according to the signature mutations shows that mutations signature 3, as signature-related deficiencies homologous recombinant, it is strongly associated with disease progression (hazard ratio (log2 scale) 8:21, the 95% confidence interval 2.93 to 13.48 , p = 0.002).

Kaplan-Meier plot also shows that the BCs with signature 3 has a shorter PFS compared with those who did not sign this (median PFS (months) for signing 3 (low vs. high): 17.2 vs. 8.1, p = 0, 0026) .Mutation signature 3, found in about 30% of MBCS regardless of hormone receptor status, was associated with shorter PFS for patients with cytotoxic chemotherapy.

Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).
Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).

Modifications PARP4, XRCC3, and RAD51 Gene Polymorphism on the relationship between Bisphenol A Exposure and liver abnormalities.

repair genes may play an important role in the relationship between environmental exposures and health outcomes. However, no evidence was available about the effect of genetic polymorphisms on the improvement of the relationship between bisphenol A (BPA) exposure and liver abnormalities.

Therefore, we evaluated the effect of nine polymorphism genotypes in three genes repair, poly (ADP-ribose) member polymerase family of 4 (PARP4), X-ray repair cross-complementary 3 (XRCC3), and RAD51 recombinase (RAD51), in relation between exposure to BPA and heart abnormalities using repeated measures of data for the elderly population.

A significant association between BPA levels and liver abnormalities are found only in elders with PARP4 haplotype GCG, XRCC3 GAG haplotype, or RAD51 TAA haplotype (odds ratio (OR) = 2.16 and p = 0.0014 for PARP4; OR = 1.57 and p = 0.0249 for XRCC3; OR = 1.43 and p = 0.0422 for RAD51). Especially, PARP4 and XRCC3 showed significant interaction with BPA exposure in relation to liver abnormalities (p <0.05 for both genes). These results indicate that PARP4, XRCC3, and RAD51 gene polymorphism has the effect of modifications on the relationship between exposure to BPA and heart abnormalities.

Colorectal neuroendocrine tumors (nets) are rare neoplasms and study of colorectal nets is relatively small compared with other tumors. To better understand the pathogenesis of this tumor, we performed whole genome sequencing and follow-up verification using Sanger sequencing of colorectal and paired Nets para-tumor tissue.

PARP-1 Polyclonal Antibody

ES8376-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against PARP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-2 Polyclonal Antibody

ES4413-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against PARP-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-2 Polyclonal Antibody

ES4413-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against PARP-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-3 Polyclonal Antibody

ES4414-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against PARP-3 from Human. This antibody is tested and validated for IHC, WB, ELISA

PARP-3 Polyclonal Antibody

ES4414-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against PARP-3 from Human. This antibody is tested and validated for IHC, WB, ELISA

Polyclonal PARP (Cleaved) Antibody

APR08927G 0.1mg
EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARP (Cleaved) . This antibody is tested and proven to work in the following applications:

PARP-1 Polyclonal Antibody

ABP57383-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

ABP57383-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-1 Polyclonal Antibody

ABP57383-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1

PARP-2 Polyclonal Antibody

ABP53414-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-2 Polyclonal Antibody

ABP53414-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-2 Polyclonal Antibody

ABP53414-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200

PARP-3 Polyclonal Antibody

ABP53415-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-3 Polyclonal Antibody

ABP53415-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

PARP-3 Polyclonal Antibody

ABP53415-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

RD-PARP-Hu-48Tests 48 Tests
EUR 478

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

RD-PARP-Hu-96Tests 96 Tests
EUR 662

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

RD-PARP-Mu-48Tests 48 Tests
EUR 533

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

RD-PARP-Mu-96Tests 96 Tests
EUR 740

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

DLR-PARP-Hu-48T 48T
EUR 479
Description: A sandwich quantitative ELISA assay kit for detection of Human Poly ADP Ribose Polymerase (PARP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

DLR-PARP-Hu-96T 96T
EUR 621
Description: A sandwich quantitative ELISA assay kit for detection of Human Poly ADP Ribose Polymerase (PARP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

DLR-PARP-Mu-48T 48T
EUR 527
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Poly ADP Ribose Polymerase (PARP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

DLR-PARP-Mu-96T 96T
EUR 688
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Poly ADP Ribose Polymerase (PARP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

RDR-PARP-Hu-48Tests 48 Tests
EUR 500

Human Poly ADP Ribose Polymerase (PARP) ELISA Kit

RDR-PARP-Hu-96Tests 96 Tests
EUR 692

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

RDR-PARP-Mu-48Tests 48 Tests
EUR 557

Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit

RDR-PARP-Mu-96Tests 96 Tests
EUR 774

Polyclonal Cleaved PARP (Asp214) Antibody

APG02631G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cleaved PARP (Asp214) . This antibody is tested and proven to work in the following applications:

PARP Antibody

48838-100ul 100ul
EUR 333

PARP Antibody

48838-50ul 50ul
EUR 239

PARP antibody

BF0719 200ul
EUR 376
Description: PARP mouse monoclonal antibody detects endogenous levels of total PPAR.

PARP antibody

10R-8001 100 ul
EUR 503
Description: Mouse monoclonal PARP antibody

PARP antibody

10R-8057 100 ug
EUR 470
Description: Mouse polyclonal PARP antibody

PARP antibody

10R-2170 100 ul
EUR 403
Description: Mouse monoclonal PARP antibody

PARP antibody

20R-1423 100 ug
EUR 673
Description: Rabbit polyclonal PARP antibody

PARP antibody

70R-30801 100 ug
EUR 327
Description: Rabbit polyclonal PARP antibody

PARP antibody

70R-30803 100 ug
EUR 327
Description: Rabbit polyclonal PARP antibody

PARP antibody

70R-11555 100 ug
EUR 404
Description: Rabbit polyclonal PARP antibody

PARP antibody

70R-11640 100 ug
EUR 611
Description: Rabbit polyclonal PARP antibody

PARP antibody

70R-11641 100 ug
EUR 581
Description: Rabbit polyclonal PARP antibody

PARP Antibody

3002-100
EUR 316

PARP Antibody

3002-30T
EUR 146

PARP-1 (Acetyl-K521) Polyclonal Antibody

ES8828-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against PARP-1 (Acetyl-K521) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

PARP-1 (Acetyl-K521) Polyclonal Antibody

ES8828-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against PARP-1 (Acetyl-K521) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cleaved-PARP-1 (G215) Polyclonal Antibody

ES1052-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (G215) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cleaved-PARP-1 (G215) Polyclonal Antibody

ES1052-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (G215) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cleaved-PARP-1 (D214) Polyclonal Antibody

ES1071-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (D214) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Cleaved-PARP-1 (D214) Polyclonal Antibody

ES1071-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (D214) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Cleaved-PARP-1 (G215) Polyclonal Antibody

ABP50053-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250

Cleaved-PARP-1 (G215) Polyclonal Antibody

ABP50053-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250

Cleaved-PARP-1 (G215) Polyclonal Antibody

ABP50053-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP50072-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP50072-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220

Cleaved-PARP-1 (D214) Polyclonal Antibody

ABP50072-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

PARP-1 (Acetyl-K521) Polyclonal Antibody

ABP59832-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521

Cleaved-PARP-1 (G215) Polyclonal Antibody

40519-100ul 100ul
EUR 252

Cleaved-PARP-1 (G215) Polyclonal Antibody

40519-50ul 50ul
EUR 187

Cleaved-PARP-1 (D214) Polyclonal Antibody

40520-100ul 100ul
EUR 252

Cleaved-PARP-1 (D214) Polyclonal Antibody

40520-50ul 50ul
EUR 187

PARP-1 (Acetyl-K521) Polyclonal Antibody

HW188-100ul 100ul
EUR 252

PARP-1 (Acetyl-K521) Polyclonal Antibody

HW188-50ul 50ul
EUR 187

PARP Monoclonal Antibody

EM1131-100ul 100ul
EUR 279
Description: A Mouse Monoclonal antibody against PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

PARP Monoclonal Antibody

EM1131-50ul 50ul
EUR 207
Description: A Mouse Monoclonal antibody against PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Cleaved-PARP antibody

29033-100ul 100ul
EUR 252

PARP Monoclonal Antibody

ABM40131-003ml 0.03ml
EUR 158
Description: A monoclonal antibody for detection of PARP from Human. This PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

PARP Monoclonal Antibody

ABM40131-01ml 0.1ml
EUR 289
Description: A monoclonal antibody for detection of PARP from Human. This PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

PARP Monoclonal Antibody

ABM40131-02ml 0.2ml
EUR 414
Description: A monoclonal antibody for detection of PARP from Human. This PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Antibody

abx020094-100ug 100 ug
EUR 439

Anti-PARP antibody

STJ97033 200 µl
EUR 197
Description: Mouse monoclonal to PARP.

Cleaved PARP Antibody

48805-100ul 100ul
EUR 333

Cleaved PARP Antibody

48805-50ul 50ul
EUR 239

Cleaved-PARP Antibody

AF7023 200ul
EUR 376
Description: PARP (Cleaved-Asp214) Antibody detects endogenous levels of fragment of activated PARP resulting from cleavage adjacent to Asp214.

Cleaved-PARP Antibody

BF9106 200ul
EUR 376
Description: The Cleaved PARP Mouse mAb can recognize endogenous pro and active PARP proteins.

Cleaved- PARP antibody

ABF7023 100 ug
EUR 438

PARP (Cleaved) Antibody

3140-100
EUR 468

PARP (Cleaved) Antibody

3141-100
EUR 446

PARP/ Rat PARP ELISA Kit

ELA-E0947r 96 Tests
EUR 886

Cleaved-PARP-1 (D214) Polyclonal Conjugated Antibody

C40520 100ul
EUR 397

IL-4 Interleukin 4 Human Recombinant Protein, Yeast

PROTP05112-4 Regular: 10ug
EUR 317
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

Monoclonal antibody for PARP

SMC-259D 0.1ml
EUR 314
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is not conjugated.

Monoclonal antibody for PARP

SMC-259D-A390 0.1ml
EUR 361
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 390.

Monoclonal antibody for PARP

SMC-259D-A488 0.1ml
EUR 360
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 488.

Monoclonal antibody for PARP

SMC-259D-A565 0.1ml
EUR 360
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 565.

Monoclonal antibody for PARP

SMC-259D-A594 0.1ml
EUR 360
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 594.

Monoclonal antibody for PARP

SMC-259D-A633 0.1ml
EUR 360
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 633.

Monoclonal antibody for PARP

SMC-259D-A655 0.1ml
EUR 360
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 655.

Monoclonal antibody for PARP

SMC-259D-A680 0.1ml
EUR 360
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 680.

Monoclonal antibody for PARP

SMC-259D-A700 0.1ml
EUR 360
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with ATTO 700.

Monoclonal antibody for PARP

SMC-259D-ALP 0.1ml
EUR 355
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Alkaline Phosphatase.

Monoclonal antibody for PARP

SMC-259D-APC 0.1ml
EUR 359
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with APC.

Monoclonal antibody for PARP

SMC-259D-APCCY7 0.1ml
EUR 432
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with APC/Cy7.

Monoclonal antibody for PARP

SMC-259D-BI 0.1ml
EUR 357
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Biotin.

Monoclonal antibody for PARP

SMC-259D-DY350 0.1ml
EUR 436
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 350.

Monoclonal antibody for PARP

SMC-259D-DY405 0.1ml
EUR 412
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 405.

Monoclonal antibody for PARP

SMC-259D-DY488 0.1ml
EUR 393
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 488.

Monoclonal antibody for PARP

SMC-259D-DY594 0.1ml
EUR 397
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 594.

Monoclonal antibody for PARP

SMC-259D-DY633 0.1ml
EUR 387
Description: A monoclonal antibody from clone M3 against Human | Mouse PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Dylight 633.

Monoclonal antibody for PARP

SMC-259D-FITC 0.1ml
EUR 353
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with FITC.

Monoclonal antibody for PARP

SMC-259D-HRP 0.1ml
EUR 349
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with HRP.

Monoclonal antibody for PARP

SMC-259D-P594 0.1ml
EUR 367
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with PE/ATTO 594.

Monoclonal antibody for PARP

SMC-259D-PCP 0.1ml
EUR 359
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with PerCP.

Monoclonal antibody for PARP

SMC-259D-RPE 0.1ml
EUR 358
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with RPE.

Monoclonal antibody for PARP

SMC-259D-STR 0.1ml
EUR 359
Description: A monoclonal antibody from clone M3 against Human | Mouse | Rat PARP. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human A synthesized peptide derived from human PARP. The antibody is tested and validated for WB assays with the following recommended dilutions: WB (1:2000). This MAb for PARP is conjugated with Streptavidin.

Anti-PARP/PARP1 Antibody

PA2227 100ug/vial
EUR 294

Anti-PARP/PARP1 Antibody

PB9309 100ug/vial
EUR 334

Cleaved PARP Monoclonal Antibody

EM1132-100ul 100ul
EUR 279
Description: A Mouse Monoclonal antibody against Cleaved PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Cleaved PARP Monoclonal Antibody

EM1132-50ul 50ul
EUR 207
Description: A Mouse Monoclonal antibody against Cleaved PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Cleaved PARP Monoclonal Antibody

EM1145-100ul 100ul
EUR 279
Description: A Mouse Monoclonal antibody against Cleaved PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Cleaved PARP Monoclonal Antibody

EM1145-50ul 50ul
EUR 207
Description: A Mouse Monoclonal antibody against Cleaved PARP from Human. This antibody is tested and validated for WB, ELISA, IHC

Human PARP-2 Antibody

32035-05111 150 ug
EUR 261

Anti-PARP-1 Antibody

A00122-1 100ul
EUR 397
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.

Anti-PARP-3 Antibody

A03762 100ul
EUR 522
Description: Rabbit Polyclonal PARP-3 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse.

Cleaved PARP Monoclonal Antibody

ABM40132-003ml 0.03ml
EUR 158
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40132-01ml 0.1ml
EUR 289
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40132-02ml 0.2ml
EUR 414
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40145-003ml 0.03ml
EUR 158
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40145-01ml 0.1ml
EUR 289
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Cleaved PARP Monoclonal Antibody

ABM40145-02ml 0.2ml
EUR 414
Description: A monoclonal antibody for detection of Cleaved PARP from Human. This Cleaved PARP antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Anti-PARP-2 Antibody

A03270-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for PARP-2 Antibody (PARP2) detection. Tested with WB in Human, Mouse.

PARP (Cleaved-Asp214) Antibody

20-abx015613
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

PARP (Cleaved-Gly215) Antibody

20-abx015614
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Anti-Cleaved PARP antibody

STJ97034 200 µl
EUR 197
Description: Mouse monoclonal to Cleaved PARP.

Anti-Cleaved PARP antibody

STJ97047 200 µl
EUR 197
Description: Cleaved-PARP-1 is a protein encoded by the PARP1 gene which is approximately 113 kDa. Cleaved-PARP-1 is localised to the nucleus. It is involved in telomere C-strand synthesis, transcription-coupled nucleotide excision repair and survival caspase cascades. It is a chromatin-associated enzyme, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is DNA dependent and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation. It also pays a role in the regulation of the molecular events involved in the recovery of cell from DNA damage. Cleaved-PARP-1 is expressed in the nervous system, liver, intestine, lung and eye. Mutations in the PARP1 gene may result in diphtheria and hemorrhagic cystitis. The antibody STJ97047 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels Cleaved-PARP-1.

Anti-PARP-1 antibody

STJ97648 200 µl
EUR 197
Description: Rabbit polyclonal to PARP-1.

Anti-PARP-2 antibody

STJ94959 200 µl
EUR 197
Description: Rabbit polyclonal to PARP-2.

Anti-PARP-3 antibody

STJ94960 200 µl
EUR 197
Description: Rabbit polyclonal to PARP-3.

Cleaved-PARP Conjugated Antibody

C29033 100ul
EUR 397

PARP Mouse Monoclonal Antibody

38067-100ul 100ul
EUR 252

PARP Mouse Monoclonal Antibody

38067-50ul 50ul
EUR 187

PARP antibody Blocking Peptide

BF0719-BP 1mg
EUR 195

PARP recombinant monoclonal antibody

A5037 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human PARP for WB,ELISA

PARP Antibody (Clone 839120)

6659-100
EUR 403

PARP Antibody (Clone 2B6)

A1109-100
EUR 359

PARP Antibody (Clone 10H)

3000-100
EUR 370

PARP Antibody (Clone 7A10)

3023-100
EUR 403

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Human)

4-PAA279Hu01
  • EUR 232.00
  • EUR 2285.00
  • EUR 574.00
  • EUR 289.00
  • EUR 208.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Poly ADP Ribose Polymerase (PARP)

Poly ADP Ribose Polymerase (PARP) Polyclonal Antibody (Rat)

4-PAA279Ra01
  • EUR 244.00
  • EUR 2470.00
  • EUR 616.00
  • EUR 306.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Poly ADP Ribose Polymerase (PARP)

Individual Reaction Mix 4

G065-4 200 reactions
EUR 167

Feline IL-4 Recombinant Protein

R00230-4 5ug/vial
EUR 259
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Feline IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

pLenti-CLDN1 shRNA-4 Plasmid

PVTBAV04867-4 2 ug
EUR 356

anti-PARP (M3)

LF-MA20421 100 ug
EUR 354
Description: Mouse monoclonal to PARP

anti-PARP (7A10)

LF-MA30362 100 ul
EUR 486
Description: Mouse Monoclonal to PARP

Anti-PARP (3G4)

YF-MA10018 100 ug
EUR 363
Description: Mouse monoclonal to PARP

Anti-PARP (2C7)

YF-MA11839 50 ug
EUR 363
Description: Mouse monoclonal to PARP

Anti-PARP Rabbit Monoclonal Antibody

M00122 100ug/vial
EUR 397
Description: Rabbit Monoclonal PARP Antibody. Validated in IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-PARP Rabbit Monoclonal Antibody

M00122-3 100ug/vial
EUR 397
Description: Rabbit Monoclonal PARP Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Monoclonal PARP Antibody, Clone: 7A10

APR08929G 0.1ml
EUR 484
Description: A Monoclonal antibody against Human PARP. The antibodies are raised in Mouse and are from clone 7A10. This antibody is applicable in WB, FC, E

Monoclonal PARP Antibody (Clone 839120)

APR08932G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human PARP (Clone 839120). The antibodies are raised in Mouse. This antibody is applicable in WB and IHC

Anti-PARP-1 antibody (KLH)

STJ98308 100 µl
EUR 234
Description: Mouse monoclonal to PARP-1 (KLH).

We analyzed the features of the spectrum of gene mutations and mutations signature pattern, and analyzed four pathways altered by mutations of genes in pancreatic neuroendocrine tumors, including DNA damage and repair, chromatin remodeling, maintenance of telomeres and activation of mTOR signaling.