Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).

We conduct exploratory biomarker study of a phase II clinical trial of eribulin plus gemcitabine (EG) versus paclitaxel plus gemcitabine (PG) in metastatic breast cancer HER2-negative (BC) patients.We conducted targeted deep sequencing with adjustable cancer gene panel and RNA expression assay. Tumor mutation load (TMB) and mutation signature is determined based on a genetic change in a targeted area. Gene variation analysis performed by PanCancer set Immune Pathway Profiling and PanCancer Panel. Statistical analysis was performed to identify the relationship between genetic changes and clinical outcomes.Of 119 patients, 40 had a biomarker data available.

Among the 40 patients, 4 post-treatment network support them. In targeted sequencing in, FAT3 (48%) is the most frequently mutated gene, followed by PKHD1, TP53, GATA3, PARP4, and PIK3CA. In terms of gene expression, low expression of epithelial-mesenchymal transition (EMT) pathway genes associated with prolonged progression-free survival (PFS) in the group EG, while high expression of EMT pathway is associated with a good prognosis in the PG group. TMB median was 6.5 (range 2.44 to 46.34) and no association between TMB and the patient’s prognosis.

Signature mutation analysis showed that the signature of 3, 20, and 26 which are often observed in our group. Survival analysis Furthermore, according to the signature mutations shows that mutations signature 3, as signature-related deficiencies homologous recombinant, it is strongly associated with disease progression (hazard ratio (log2 scale) 8:21, the 95% confidence interval 2.93 to 13.48 , p = 0.002).

Kaplan-Meier plot also shows that the BCs with signature 3 has a shorter PFS compared with those who did not sign this (median PFS (months) for signing 3 (low vs. high): 17.2 vs. 8.1, p = 0, 0026) .Mutation signature 3, found in about 30% of MBCS regardless of hormone receptor status, was associated with shorter PFS for patients with cytotoxic chemotherapy.

Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).
Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11).

Modifications PARP4, XRCC3, and RAD51 Gene Polymorphism on the relationship between Bisphenol A Exposure and liver abnormalities.

repair genes may play an important role in the relationship between environmental exposures and health outcomes. However, no evidence was available about the effect of genetic polymorphisms on the improvement of the relationship between bisphenol A (BPA) exposure and liver abnormalities.

Therefore, we evaluated the effect of nine polymorphism genotypes in three genes repair, poly (ADP-ribose) member polymerase family of 4 (PARP4), X-ray repair cross-complementary 3 (XRCC3), and RAD51 recombinase (RAD51), in relation between exposure to BPA and heart abnormalities using repeated measures of data for the elderly population.

A significant association between BPA levels and liver abnormalities are found only in elders with PARP4 haplotype GCG, XRCC3 GAG haplotype, or RAD51 TAA haplotype (odds ratio (OR) = 2.16 and p = 0.0014 for PARP4; OR = 1.57 and p = 0.0249 for XRCC3; OR = 1.43 and p = 0.0422 for RAD51). Especially, PARP4 and XRCC3 showed significant interaction with BPA exposure in relation to liver abnormalities (p <0.05 for both genes). These results indicate that PARP4, XRCC3, and RAD51 gene polymorphism has the effect of modifications on the relationship between exposure to BPA and heart abnormalities.

Colorectal neuroendocrine tumors (nets) are rare neoplasms and study of colorectal nets is relatively small compared with other tumors. To better understand the pathogenesis of this tumor, we performed whole genome sequencing and follow-up verification using Sanger sequencing of colorectal and paired Nets para-tumor tissue.

PARP-4 Polyclonal Antibody
ES4835-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against PARP-4 from Human. This antibody is tested and validated for IHC, WB, ELISA
Anti-PARP-4 antibody
STJ94961 200 µl
EUR 197
Description: Rabbit polyclonal to PARP-4.
Polyclonal PARP Antibody
APR08928G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARP . This antibody is tested and proven to work in the following applications:
Polyclonal PARP (Cleaved) Antibody
APR08927G 0.1mg
EUR 528
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARP (Cleaved) . This antibody is tested and proven to work in the following applications:
PARP-2 Polyclonal Antibody
ABP53414-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200
PARP-2 Polyclonal Antibody
ABP53414-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200
PARP-2 Polyclonal Antibody
ABP53414-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-2 from Human, Mouse. This PARP-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-2 at AA rangle: 120-200
PARP-3 Polyclonal Antibody
ABP53415-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90
PARP-3 Polyclonal Antibody
ABP53415-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90
PARP-3 Polyclonal Antibody
ABP53415-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-3 from Human. This PARP-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARP-3 at AA rangle: 10-90
PARP-1 Polyclonal Antibody
ABP57383-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-1
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1
PARP-1 Polyclonal Antibody
ABP57383-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-1
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1
PARP-1 Polyclonal Antibody
ABP57383-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-1
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-1 from Human, Mouse, Rat. This PARP-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1
PARP-1 Polyclonal Antibody
ES8376-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against PARP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA
PARP-1 Polyclonal Antibody
ES8376-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against PARP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA
PARP-2 Polyclonal Antibody
ES4413-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against PARP-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA
PARP-2 Polyclonal Antibody
ES4413-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against PARP-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA
PARP-3 Polyclonal Antibody
ES4414-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against PARP-3 from Human. This antibody is tested and validated for IHC, WB, ELISA
PARP-3 Polyclonal Antibody
ES4414-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against PARP-3 from Human. This antibody is tested and validated for IHC, WB, ELISA
Human Poly ADP Ribose Polymerase (PARP) ELISA Kit
DLR-PARP-Hu-48T 48T
EUR 479
  • Should the Human Poly ADP Ribose Polymerase (PARP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Poly ADP Ribose Polymerase (PARP) in samples from tissue homogenates, cell lysates or other biological fluids.
Human Poly ADP Ribose Polymerase (PARP) ELISA Kit
DLR-PARP-Hu-96T 96T
EUR 621
  • Should the Human Poly ADP Ribose Polymerase (PARP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Poly ADP Ribose Polymerase (PARP) in samples from tissue homogenates, cell lysates or other biological fluids.
Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit
DLR-PARP-Mu-48T 48T
EUR 527
  • Should the Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Poly ADP Ribose Polymerase (PARP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit
DLR-PARP-Mu-96T 96T
EUR 688
  • Should the Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Poly ADP Ribose Polymerase (PARP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human Poly ADP Ribose Polymerase (PARP) ELISA Kit
RDR-PARP-Hu-48Tests 48 Tests
EUR 500
Human Poly ADP Ribose Polymerase (PARP) ELISA Kit
RDR-PARP-Hu-96Tests 96 Tests
EUR 692
Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit
RDR-PARP-Mu-48Tests 48 Tests
EUR 557
Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit
RDR-PARP-Mu-96Tests 96 Tests
EUR 774
Human Poly ADP Ribose Polymerase (PARP) ELISA Kit
RD-PARP-Hu-48Tests 48 Tests
EUR 478
Human Poly ADP Ribose Polymerase (PARP) ELISA Kit
RD-PARP-Hu-96Tests 96 Tests
EUR 662
Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit
RD-PARP-Mu-48Tests 48 Tests
EUR 533
Mouse Poly ADP Ribose Polymerase (PARP) ELISA Kit
RD-PARP-Mu-96Tests 96 Tests
EUR 740
Polyclonal Cleaved PARP (Asp214) Antibody
APG02631G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cleaved PARP (Asp214) . This antibody is tested and proven to work in the following applications:
PARP Antibody
3002-100
EUR 316
PARP Antibody
3002-30T
EUR 146
PARP antibody
20R-1423 100 ug
EUR 673
Description: Rabbit polyclonal PARP antibody
PARP antibody
70R-11555 100 ug
EUR 404
Description: Rabbit polyclonal PARP antibody
PARP antibody
70R-11640 100 ug
EUR 611
Description: Rabbit polyclonal PARP antibody
PARP antibody
70R-11641 100 ug
EUR 581
Description: Rabbit polyclonal PARP antibody
PARP antibody
70R-30801 100 ug
EUR 327
Description: Rabbit polyclonal PARP antibody
PARP antibody
70R-30803 100 ug
EUR 327
Description: Rabbit polyclonal PARP antibody
PARP antibody
10R-2170 100 ul
EUR 403
Description: Mouse monoclonal PARP antibody
PARP antibody
10R-8001 100 ul
EUR 503
Description: Mouse monoclonal PARP antibody
PARP antibody
10R-8057 100 ug
EUR 470
Description: Mouse polyclonal PARP antibody
PARP Antibody
48838-100ul 100ul
EUR 333
PARP Antibody
48838-50ul 50ul
EUR 239
PARP antibody
BF0719 200ul
EUR 376
Description: PARP mouse monoclonal antibody detects endogenous levels of total PPAR.
Cleaved-PARP-1 (G215) Polyclonal Antibody
40519-100ul 100ul
EUR 252
Cleaved-PARP-1 (G215) Polyclonal Antibody
40519-50ul 50ul
EUR 187
Cleaved-PARP-1 (D214) Polyclonal Antibody
40520-100ul 100ul
EUR 252
Cleaved-PARP-1 (D214) Polyclonal Antibody
40520-50ul 50ul
EUR 187
Cleaved-PARP-1 (G215) Polyclonal Antibody
ABP50053-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250
  • Applications tips:
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250
Cleaved-PARP-1 (G215) Polyclonal Antibody
ABP50053-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250
  • Applications tips:
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250
Cleaved-PARP-1 (G215) Polyclonal Antibody
ABP50053-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250
  • Applications tips:
Description: A polyclonal antibody for detection of Cleaved-PARP-1 G215) from Human. This Cleaved-PARP-1 G215) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 170-250
Cleaved-PARP-1 (D214) Polyclonal Antibody
ABP50072-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220
  • Applications tips:
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220
Cleaved-PARP-1 (D214) Polyclonal Antibody
ABP50072-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220
  • Applications tips:
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220
Cleaved-PARP-1 (D214) Polyclonal Antibody
ABP50072-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220
  • Applications tips:
Description: A polyclonal antibody for detection of Cleaved-PARP-1 D214) from Human, Mouse. This Cleaved-PARP-1 D214) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PARP-1 at AA range: 140-220
PARP-1 (Acetyl-K521) Polyclonal Antibody
ABP59832-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521
PARP-1 (Acetyl-K521) Polyclonal Antibody
ABP59832-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521
PARP-1 (Acetyl-K521) Polyclonal Antibody
ABP59832-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521
  • Applications tips:
Description: A polyclonal antibody for detection of PARP-1 Acetyl-K521) from Human, Mouse, Rat. This PARP-1 Acetyl-K521) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human PARP-1 (Acetyl-K521) protein at amino acid sequence of K521
PARP-1 (Acetyl-K521) Polyclonal Antibody
HW188-100ul 100ul
EUR 252
PARP-1 (Acetyl-K521) Polyclonal Antibody
HW188-50ul 50ul
EUR 187
PARP-1 (Acetyl-K521) Polyclonal Antibody
ES8828-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against PARP-1 (Acetyl-K521) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA
PARP-1 (Acetyl-K521) Polyclonal Antibody
ES8828-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against PARP-1 (Acetyl-K521) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA
Cleaved-PARP-1 (D214) Polyclonal Antibody
ES1071-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (D214) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA
Cleaved-PARP-1 (D214) Polyclonal Antibody
ES1071-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (D214) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA
Cleaved-PARP-1 (G215) Polyclonal Antibody
ES1052-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (G215) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA
Cleaved-PARP-1 (G215) Polyclonal Antibody
ES1052-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Cleaved-PARP-1 (G215) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA
Cleaved-PARP antibody
29033-100ul 100ul
EUR 252
PARP (Cleaved) Antibody
3140-100
EUR 468
PARP (Cleaved) Antibody
3141-100
EUR 446
Cleaved PARP Antibody
48805-100ul 100ul
EUR 333
Cleaved PARP Antibody
48805-50ul 50ul
EUR 239
Cleaved PARP Antibody
abx020094-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.
Cleaved-PARP Antibody
AF7023 200ul
EUR 376
Description: PARP (Cleaved-Asp214) Antibody detects endogenous levels of fragment of activated PARP resulting from cleavage adjacent to Asp214.
Cleaved-PARP Antibody
BF9106 200ul
EUR 376
Description: The Cleaved PARP Mouse mAb can recognize endogenous pro and active PARP proteins.
Cleaved- PARP antibody
ABF7023 100 ug
EUR 438
PARP Monoclonal Antibody
ABM40131-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of PARP from Human. This PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide
PARP Monoclonal Antibody
ABM40131-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of PARP from Human. This PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide
PARP Monoclonal Antibody
ABM40131-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of PARP from Human. This PARP antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide
PARP Monoclonal Antibody
EM1131-100ul 100ul
EUR 279
Description: A Mouse Monoclonal antibody against PARP from Human. This antibody is tested and validated for WB, ELISA, IHC
PARP Monoclonal Antibody
EM1131-50ul 50ul
EUR 207
Description: A Mouse Monoclonal antibody against PARP from Human. This antibody is tested and validated for WB, ELISA, IHC
Anti-PARP antibody
STJ97033 200 µl
EUR 197
Description: Mouse monoclonal to PARP.
PARP/ Rat PARP ELISA Kit
ELA-E0947r 96 Tests
EUR 886
Cleaved-PARP-1 (D214) Polyclonal Conjugated Antibody
C40520 100ul
EUR 397
PARP Antibody (Clone 7A10)
3023-100
EUR 403
PARP Antibody (Clone 10H)
3000-100
EUR 370
PARP Antibody (Clone 839120)
6659-100
EUR 403
PARP Antibody (Clone 2B6)
A1109-100
EUR 359
Human PARP-2 Antibody
32035-05111 150 ug
EUR 261
PARP Mouse Monoclonal Antibody
38067-100ul 100ul
EUR 252
PARP Mouse Monoclonal Antibody
38067-50ul 50ul
EUR 187
Anti-PARP-2 Antibody
A03270-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for PARP-2 Antibody (PARP2) detection. Tested with WB in Human, Mouse.
Anti-PARP-3 Antibody
A03762 100ul
EUR 522
Description: Rabbit Polyclonal PARP-3 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse.
Anti-PARP-1 Antibody
A00122-1 100ul
EUR 397
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.
PARP (Cleaved-Asp214) Antibody
20-abx015613
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.
PARP (Cleaved-Gly215) Antibody
20-abx015614
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

We analyzed the features of the spectrum of gene mutations and mutations signature pattern, and analyzed four pathways altered by mutations of genes in pancreatic neuroendocrine tumors, including DNA damage and repair, chromatin remodeling, maintenance of telomeres and activation of mTOR signaling.